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Prediction of Small Molecule Inhibitors Targeting the Severe Acute Respiratory Syndrome Coronavirus-2 RNA-dependent RNA Polymerase

[Image: see text] The current COVID-19 outbreak warrants the design and development of novel anti-COVID therapeutics. Using a combination of bioinformatics and computational tools, we modelled the 3D structure of the RdRp (RNA-dependent RNA polymerase) of SARS-CoV2 (severe acute respiratory syndrome...

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Detalles Bibliográficos
Autores principales: Ahmad, Mohammed, Dwivedy, Abhisek, Mariadasse, Richard, Tiwari, Satish, Kar, Deepsikha, Jeyakanthan, Jeyaraman, Biswal, Bichitra K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7391942/
https://www.ncbi.nlm.nih.gov/pubmed/32743211
http://dx.doi.org/10.1021/acsomega.0c02096