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Predicting Treatment Outcome in Major Depressive Disorder Using Serotonin 4 Receptor PET Brain Imaging, Functional MRI, Cognitive-, EEG-Based, and Peripheral Biomarkers: A NeuroPharm Open Label Clinical Trial Protocol
BACKGROUND: Between 30 and 50% of patients with major depressive disorder (MDD) do not respond sufficiently to antidepressant regimens. The conventional pharmacological treatments predominantly target serotonergic brain signaling but better tools to predict treatment response and identify relevant s...
Autores principales: | Köhler-Forsberg, Kristin, Jorgensen, Anders, Dam, Vibeke H., Stenbæk, Dea Siggaard, Fisher, Patrick M., Ip, Cheng-Teng, Ganz, Melanie, Poulsen, Henrik Enghusen, Giraldi, Annamaria, Ozenne, Brice, Jørgensen, Martin Balslev, Knudsen, Gitte Moos, Frokjaer, Vibe Gedsoe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7391965/ https://www.ncbi.nlm.nih.gov/pubmed/32792991 http://dx.doi.org/10.3389/fpsyt.2020.00641 |
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