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M1 muscarinic acetylcholine receptor dysfunction in moderate Alzheimer’s disease pathology

Aggregation of amyloid beta and loss of cholinergic innervation in the brain are predominant components of Alzheimer’s disease pathology and likely underlie cognitive impairment. Acetylcholinesterase inhibitors are one of the few treatment options for Alzheimer’s disease, where levels of available a...

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Detalles Bibliográficos
Autores principales: Yi, Jee Hyun, Whitcomb, Daniel J, Park, Se Jin, Martinez-Perez, Celia, Barbati, Saviana A, Mitchell, Scott J, Cho, Kwangwook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7391992/
https://www.ncbi.nlm.nih.gov/pubmed/32766549
http://dx.doi.org/10.1093/braincomms/fcaa058