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DNA methylation maintains the CLDN1-EPHB6-SLUG axis to enhance chemotherapeutic efficacy and inhibit lung cancer progression

The loss of cancer-cell junctions and escape from the primary-tumor microenvironment are hallmarks of metastasis. A tight-junction protein, Claudin 1 (CLDN1), is a metastasis suppressor in lung adenocarcinoma. However, as a metastasis suppressor, the underlying molecular mechanisms of CLDN1 has not...

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Detalles Bibliográficos
Autores principales:	Wu, Jia-En, Wu, Yi-Ying, Tung, Chia-Hao, Tsai, Yao-Tsung, Chen, Hsuan-Yu, Chen, Yuh-Ling, Hong, Tse-Ming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392003/ https://www.ncbi.nlm.nih.gov/pubmed/32754286 http://dx.doi.org/10.7150/thno.45785

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