EZH2-mediated Epigenetic Silencing of miR-29/miR-30 targets LOXL4 and contributes to Tumorigenesis, Metastasis, and Immune Microenvironment Remodeling in Breast Cancer

Enhancer of Zeste Homolog 2 (EZH2), a key epigenetic regulator, is involved in breast cancer progression and metastasis. LOXL4 is increasingly recognized as an important player in cancer progression. To date, how EZH2 regulates LOXL4 in the progression of breast cancer remains unclear. Methods: We e...

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Detalles Bibliográficos
Autores principales: Yin, Huilong, Wang, Yidi, Wu, Ye, Zhang, Xiang, Zhang, Xiaofang, Liu, Jun, Wang, Ting, Fan, Jing, Sun, Jianyong, Yang, Angang, Zhang, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392008/
https://www.ncbi.nlm.nih.gov/pubmed/32754259
http://dx.doi.org/10.7150/thno.44849

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