Spatial heterogeneity of radiolabeled choline positron emission tomography in tumors of patients with non-small cell lung cancer: first-in-patient evaluation of [(18)F]fluoromethyl-(1,2-(2)H(4))-choline

Purpose: The spatio-molecular distribution of choline and its metabolites in tumors is highly heterogeneous. Due to regulation of choline metabolism by hypoxic transcriptional signaling and other survival factors, we envisage that detection of such heterogeneity in patient tumors could provide the b...

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Detalles Bibliográficos
Autores principales: Dubash, Suraiya, Inglese, Marianna, Mauri, Francesco, Kozlowski, Kasia, Trivedi, Pritesh, Arshad, Mubarik, Challapalli, Amarnath, Barwick, Tara, Al-Nahhas, Adil, Stanbridge, Rex, Lewanski, Conrad, Berry, Matthew, Bowen, Frances, Aboagye, Eric O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392021/
https://www.ncbi.nlm.nih.gov/pubmed/32754271
http://dx.doi.org/10.7150/thno.47298

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392021/
https://www.ncbi.nlm.nih.gov/pubmed/32754271
http://dx.doi.org/10.7150/thno.47298

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