E3 ligase ZFP91 inhibits Hepatocellular Carcinoma Metabolism Reprogramming by regulating PKM splicing

Rationale: Hepatocellular carcinoma (HCC) is one of the most lethal cancers, and few molecularly targeted anticancer therapies have been developed to treat it. Thus, the identification of new therapeutic targets is urgent. Metabolic reprogramming is an important hallmark of cancer. However, how ubiq...

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Detalles Bibliográficos
Autores principales: Chen, De, Wang, Yanjie, Lu, Ruixun, Jiang, Xiaofeng, Chen, Xinhui, Meng, Nan, Chen, Min, Xie, Shan, Yan, Guang-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392027/
https://www.ncbi.nlm.nih.gov/pubmed/32754263
http://dx.doi.org/10.7150/thno.44873

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