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Identification and estimation of the SEIRD epidemic model for COVID-19

This paper studies the SEIRD epidemic model for COVID-19. First, I show that the model is poorly identified from the observed number of deaths and confirmed cases. There are many sets of parameters that are observationally equivalent in the short run but lead to markedly different long run forecasts...

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Autor principal: Korolev, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392128/
https://www.ncbi.nlm.nih.gov/pubmed/32836680
http://dx.doi.org/10.1016/j.jeconom.2020.07.038
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author Korolev, Ivan
author_facet Korolev, Ivan
author_sort Korolev, Ivan
collection PubMed
description This paper studies the SEIRD epidemic model for COVID-19. First, I show that the model is poorly identified from the observed number of deaths and confirmed cases. There are many sets of parameters that are observationally equivalent in the short run but lead to markedly different long run forecasts. Second, I show that the basic reproduction number [Formula: see text] can be identified from the data, conditional on epidemiologic parameters, and propose several nonlinear SUR approaches to estimate [Formula: see text]. I examine the performance of these methods using Monte Carlo studies and demonstrate that they yield fairly accurate estimates of [Formula: see text]. Next, I apply these methods to estimate [Formula: see text] for the US, California, and Japan, and document heterogeneity in the value of [Formula: see text] across regions. My estimation approach accounts for possible underreporting of the number of cases. I demonstrate that if one fails to take underreporting into account and estimates [Formula: see text] from the reported cases data, the resulting estimate of [Formula: see text] may be biased downward and the resulting forecasts may exaggerate the long run number of deaths. Finally, I discuss how auxiliary information from random tests can be used to calibrate the initial parameters of the model and narrow down the range of possible forecasts of the future number of deaths.
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spelling pubmed-73921282020-07-31 Identification and estimation of the SEIRD epidemic model for COVID-19 Korolev, Ivan J Econom Article This paper studies the SEIRD epidemic model for COVID-19. First, I show that the model is poorly identified from the observed number of deaths and confirmed cases. There are many sets of parameters that are observationally equivalent in the short run but lead to markedly different long run forecasts. Second, I show that the basic reproduction number [Formula: see text] can be identified from the data, conditional on epidemiologic parameters, and propose several nonlinear SUR approaches to estimate [Formula: see text]. I examine the performance of these methods using Monte Carlo studies and demonstrate that they yield fairly accurate estimates of [Formula: see text]. Next, I apply these methods to estimate [Formula: see text] for the US, California, and Japan, and document heterogeneity in the value of [Formula: see text] across regions. My estimation approach accounts for possible underreporting of the number of cases. I demonstrate that if one fails to take underreporting into account and estimates [Formula: see text] from the reported cases data, the resulting estimate of [Formula: see text] may be biased downward and the resulting forecasts may exaggerate the long run number of deaths. Finally, I discuss how auxiliary information from random tests can be used to calibrate the initial parameters of the model and narrow down the range of possible forecasts of the future number of deaths. Elsevier B.V. 2021-01 2020-07-30 /pmc/articles/PMC7392128/ /pubmed/32836680 http://dx.doi.org/10.1016/j.jeconom.2020.07.038 Text en © 2020 Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Korolev, Ivan
Identification and estimation of the SEIRD epidemic model for COVID-19
title Identification and estimation of the SEIRD epidemic model for COVID-19
title_full Identification and estimation of the SEIRD epidemic model for COVID-19
title_fullStr Identification and estimation of the SEIRD epidemic model for COVID-19
title_full_unstemmed Identification and estimation of the SEIRD epidemic model for COVID-19
title_short Identification and estimation of the SEIRD epidemic model for COVID-19
title_sort identification and estimation of the seird epidemic model for covid-19
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392128/
https://www.ncbi.nlm.nih.gov/pubmed/32836680
http://dx.doi.org/10.1016/j.jeconom.2020.07.038
work_keys_str_mv AT korolevivan identificationandestimationoftheseirdepidemicmodelforcovid19