Cargando…
Intestinal Epithelial Cells Express Immunomodulatory ISG15 During Active Ulcerative Colitis and Crohn’s Disease
BACKGROUND AND AIMS: Intestinal epithelial cells [IECs] secrete cytokines that recruit immune cells to the mucosa and regulate immune responses that drive inflammation in inflammatory bowel disease [IBD]. However, experiments in patient-derived IEC models are still scarce. Here, we aimed to investig...
Autores principales: | Østvik, Ann Elisabet, Svendsen, Tarjei Dahl, Granlund, Atle van Beelen, Doseth, Berit, Skovdahl, Helene Kolstad, Bakke, Ingunn, Thorsvik, Silje, Afroz, Wahida, Walaas, Gunnar Andreas, Mollnes, Tom Eirik, Gustafsson, Björn Inge, Sandvik, Arne Kristian, Bruland, Torunn |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392169/ https://www.ncbi.nlm.nih.gov/pubmed/32020185 http://dx.doi.org/10.1093/ecco-jcc/jjaa022 |
Ejemplares similares
-
C-C Motif Ligand 20 (CCL20) and C-C Motif Chemokine Receptor 6 (CCR6) in Human Peripheral Blood Mononuclear Cells: Dysregulated in Ulcerative Colitis and a Potential Role for CCL20 in IL-1β Release
por: Skovdahl, Helene Kolstad, et al.
Publicado: (2018) -
Patient Derived Colonoids as Drug Testing Platforms–Critical Importance of Oxygen Concentration
por: Skovdahl, Helene Kolstad, et al.
Publicado: (2021) -
Ulcer‐associated cell lineage expresses genes involved in regeneration and is hallmarked by high neutrophil gelatinase‐associated lipocalin (NGAL) levels
por: Thorsvik, Silje, et al.
Publicado: (2019) -
Mucosal and faecal neutrophil gelatinase-associated lipocalin as potential biomarkers for collagenous colitis
por: Bakke, Ingunn, et al.
Publicado: (2021) -
Expression of CCL20 and Its Corresponding Receptor CCR6 Is Enhanced in Active Inflammatory Bowel Disease, and TLR3 Mediates CCL20 Expression in Colonic Epithelial Cells
por: Skovdahl, Helene Kolstad, et al.
Publicado: (2015)