A Pilot Integrative Analysis of Colonic Gene Expression, Gut Microbiota, and Immune Infiltration in Primary Sclerosing Cholangitis-Inflammatory Bowel Disease: Association of Disease With Bile Acid Pathways

BACKGROUND: Although a majority of patients with PSC have colitis [PSC-IBD; primary sclerosing cholangitis-inflammatory bowel disease], this is phenotypically different from ulcerative colitis [UC]. We sought to define further the pathophysiological differences between PSC-IBD and UC, by applying a...

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Detalles Bibliográficos
Autores principales: Quraishi, Mohammed Nabil, Acharjee, Animesh, Beggs, Andrew D, Horniblow, Richard, Tselepis, Chris, Gkoutos, Georgios, Ghosh, Subrata, Rossiter, A E, Loman, Nicholas, van Schaik, Willem, Withers, David, Walters, Julian R F, Hirschfield, Gideon M, Iqbal, Tariq H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392170/
https://www.ncbi.nlm.nih.gov/pubmed/32016358
http://dx.doi.org/10.1093/ecco-jcc/jjaa021

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