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Should a viral genome stay in the host cell or leave? A quantitative dynamics study of how hepatitis C virus deals with this dilemma

Virus proliferation involves gene replication inside infected cells and transmission to new target cells. Once positive-strand RNA virus has infected a cell, the viral genome serves as a template for copying (“stay-strategy”) or is packaged into a progeny virion that will be released extracellularly...

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Detalles Bibliográficos
Autores principales: Iwanami, Shoya, Kitagawa, Kosaku, Ohashi, Hirofumi, Asai, Yusuke, Shionoya, Kaho, Saso, Wakana, Nishioka, Kazane, Inaba, Hisashi, Nakaoka, Shinji, Wakita, Takaji, Diekmann, Odo, Iwami, Shingo, Watashi, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392214/
https://www.ncbi.nlm.nih.gov/pubmed/32730280
http://dx.doi.org/10.1371/journal.pbio.3000562

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