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Enacting national social distancing policies corresponds with dramatic reduction in COVID19 infection rates

The outbreak the SARS-CoV-2 (CoV-2) virus has resulted in over 6.5 million cases of COVID19, greatly stressing global healthcare infrastructure. Lacking medical prophylactic measures to combat disease spread, many nations have adopted social distancing policies in order to mitigate transmission of C...

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Autores principales: McGrail, Daniel J., Dai, Jianli, McAndrews, Kathleen M., Kalluri, Raghu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392246/
https://www.ncbi.nlm.nih.gov/pubmed/32730356
http://dx.doi.org/10.1371/journal.pone.0236619
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author McGrail, Daniel J.
Dai, Jianli
McAndrews, Kathleen M.
Kalluri, Raghu
author_facet McGrail, Daniel J.
Dai, Jianli
McAndrews, Kathleen M.
Kalluri, Raghu
author_sort McGrail, Daniel J.
collection PubMed
description The outbreak the SARS-CoV-2 (CoV-2) virus has resulted in over 6.5 million cases of COVID19, greatly stressing global healthcare infrastructure. Lacking medical prophylactic measures to combat disease spread, many nations have adopted social distancing policies in order to mitigate transmission of CoV-2. While mathematical models have suggested the efficacy of social distancing to curb the spread of CoV-2, there is a lack of systematic studies to quantify the real-world efficacy of these approaches. Here, we first demonstrate that implementation of social distancing policies in US states corresponded with a reduction in COVID19 spread rates, and that the reduction in spread rate is proportional to the average change in mobility. We validate this observation on a worldwide scale by analyzing COVID19 spread rate in 134 nations with varying social distancing policies. Globally, we find that social distancing policies significantly reduced the COVID19 spread rate, with resulting in an estimated 65% reduction (95% CI = 39–80%) in new COVID19 cases over a two week time period. These data suggest that social distancing policies may be a powerful tool to prevent spread of COVID19 in real-world scenarios.
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spelling pubmed-73922462020-08-05 Enacting national social distancing policies corresponds with dramatic reduction in COVID19 infection rates McGrail, Daniel J. Dai, Jianli McAndrews, Kathleen M. Kalluri, Raghu PLoS One Research Article The outbreak the SARS-CoV-2 (CoV-2) virus has resulted in over 6.5 million cases of COVID19, greatly stressing global healthcare infrastructure. Lacking medical prophylactic measures to combat disease spread, many nations have adopted social distancing policies in order to mitigate transmission of CoV-2. While mathematical models have suggested the efficacy of social distancing to curb the spread of CoV-2, there is a lack of systematic studies to quantify the real-world efficacy of these approaches. Here, we first demonstrate that implementation of social distancing policies in US states corresponded with a reduction in COVID19 spread rates, and that the reduction in spread rate is proportional to the average change in mobility. We validate this observation on a worldwide scale by analyzing COVID19 spread rate in 134 nations with varying social distancing policies. Globally, we find that social distancing policies significantly reduced the COVID19 spread rate, with resulting in an estimated 65% reduction (95% CI = 39–80%) in new COVID19 cases over a two week time period. These data suggest that social distancing policies may be a powerful tool to prevent spread of COVID19 in real-world scenarios. Public Library of Science 2020-07-30 /pmc/articles/PMC7392246/ /pubmed/32730356 http://dx.doi.org/10.1371/journal.pone.0236619 Text en © 2020 McGrail et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
McGrail, Daniel J.
Dai, Jianli
McAndrews, Kathleen M.
Kalluri, Raghu
Enacting national social distancing policies corresponds with dramatic reduction in COVID19 infection rates
title Enacting national social distancing policies corresponds with dramatic reduction in COVID19 infection rates
title_full Enacting national social distancing policies corresponds with dramatic reduction in COVID19 infection rates
title_fullStr Enacting national social distancing policies corresponds with dramatic reduction in COVID19 infection rates
title_full_unstemmed Enacting national social distancing policies corresponds with dramatic reduction in COVID19 infection rates
title_short Enacting national social distancing policies corresponds with dramatic reduction in COVID19 infection rates
title_sort enacting national social distancing policies corresponds with dramatic reduction in covid19 infection rates
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392246/
https://www.ncbi.nlm.nih.gov/pubmed/32730356
http://dx.doi.org/10.1371/journal.pone.0236619
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