Doxycycline and Sitafloxacin Combination Therapy for Treating Highly Resistant Mycoplasma genitalium

Antimicrobial-resistant Mycoplasma genitalium is becoming increasingly common and creating major treatment challenges. We present early data on combination therapy with doxycycline and sitafloxacin to treat highly resistant M. genitalium. We found the regimen was well tolerated and cured 11/12 infec...

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Autores principales: Durukan, Duygu, Doyle, Michelle, Murray, Gerald, Bodiyabadu, Kaveesha, Vodstrcil, Lenka, Chow, Eric P.F., Jensen, Jorgen S., Fairley, Christopher K., Aguirre, Ivette, Bradshaw, Catriona S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2020
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392426/
https://www.ncbi.nlm.nih.gov/pubmed/32687029
http://dx.doi.org/10.3201/eid2608.191806
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author Durukan, Duygu
Doyle, Michelle
Murray, Gerald
Bodiyabadu, Kaveesha
Vodstrcil, Lenka
Chow, Eric P.F.
Jensen, Jorgen S.
Fairley, Christopher K.
Aguirre, Ivette
Bradshaw, Catriona S.
author_facet Durukan, Duygu
Doyle, Michelle
Murray, Gerald
Bodiyabadu, Kaveesha
Vodstrcil, Lenka
Chow, Eric P.F.
Jensen, Jorgen S.
Fairley, Christopher K.
Aguirre, Ivette
Bradshaw, Catriona S.
author_sort Durukan, Duygu
collection PubMed
description Antimicrobial-resistant Mycoplasma genitalium is becoming increasingly common and creating major treatment challenges. We present early data on combination therapy with doxycycline and sitafloxacin to treat highly resistant M. genitalium. We found the regimen was well tolerated and cured 11/12 infections that had failed prior regimens with moxifloxacin and pristinamycin.
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spelling pubmed-73924262020-08-06 Doxycycline and Sitafloxacin Combination Therapy for Treating Highly Resistant Mycoplasma genitalium Durukan, Duygu Doyle, Michelle Murray, Gerald Bodiyabadu, Kaveesha Vodstrcil, Lenka Chow, Eric P.F. Jensen, Jorgen S. Fairley, Christopher K. Aguirre, Ivette Bradshaw, Catriona S. Emerg Infect Dis Dispatch Antimicrobial-resistant Mycoplasma genitalium is becoming increasingly common and creating major treatment challenges. We present early data on combination therapy with doxycycline and sitafloxacin to treat highly resistant M. genitalium. We found the regimen was well tolerated and cured 11/12 infections that had failed prior regimens with moxifloxacin and pristinamycin. Centers for Disease Control and Prevention 2020-08 /pmc/articles/PMC7392426/ /pubmed/32687029 http://dx.doi.org/10.3201/eid2608.191806 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Durukan, Duygu
Doyle, Michelle
Murray, Gerald
Bodiyabadu, Kaveesha
Vodstrcil, Lenka
Chow, Eric P.F.
Jensen, Jorgen S.
Fairley, Christopher K.
Aguirre, Ivette
Bradshaw, Catriona S.
Doxycycline and Sitafloxacin Combination Therapy for Treating Highly Resistant Mycoplasma genitalium
title Doxycycline and Sitafloxacin Combination Therapy for Treating Highly Resistant Mycoplasma genitalium
title_full Doxycycline and Sitafloxacin Combination Therapy for Treating Highly Resistant Mycoplasma genitalium
title_fullStr Doxycycline and Sitafloxacin Combination Therapy for Treating Highly Resistant Mycoplasma genitalium
title_full_unstemmed Doxycycline and Sitafloxacin Combination Therapy for Treating Highly Resistant Mycoplasma genitalium
title_short Doxycycline and Sitafloxacin Combination Therapy for Treating Highly Resistant Mycoplasma genitalium
title_sort doxycycline and sitafloxacin combination therapy for treating highly resistant mycoplasma genitalium
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392426/
https://www.ncbi.nlm.nih.gov/pubmed/32687029
http://dx.doi.org/10.3201/eid2608.191806
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