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Characterizing Norovirus Transmission from Outbreak Data, United States
Norovirus is the leading cause of acute gastroenteritis outbreaks in the United States. We estimated the basic (R(0)) and effective (R(e)) reproduction numbers for 7,094 norovirus outbreaks reported to the National Outbreak Reporting System (NORS) during 2009–2017 and used regression models to asses...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Centers for Disease Control and Prevention
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392428/ https://www.ncbi.nlm.nih.gov/pubmed/32687043 http://dx.doi.org/10.3201/eid2608.191537 |
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author | Steele, Molly K. Wikswo, Mary E. Hall, Aron J. Koelle, Katia Handel, Andreas Levy, Karen Waller, Lance A. Lopman, Ben A. |
author_facet | Steele, Molly K. Wikswo, Mary E. Hall, Aron J. Koelle, Katia Handel, Andreas Levy, Karen Waller, Lance A. Lopman, Ben A. |
author_sort | Steele, Molly K. |
collection | PubMed |
description | Norovirus is the leading cause of acute gastroenteritis outbreaks in the United States. We estimated the basic (R(0)) and effective (R(e)) reproduction numbers for 7,094 norovirus outbreaks reported to the National Outbreak Reporting System (NORS) during 2009–2017 and used regression models to assess whether transmission varied by outbreak setting. The median R(0) was 2.75 (interquartile range [IQR] 2.38–3.65), and median R(e) was 1.29 (IQR 1.12–1.74). Long-term care and assisted living facilities had an R(0) of 3.35 (95% CI 3.26–3.45), but R(0) did not differ substantially for outbreaks in other settings, except for outbreaks in schools, colleges, and universities, which had an R(0) of 2.92 (95% CI 2.82–3.03). Seasonally, R(0) was lowest (3.11 [95% CI 2.97–3.25]) in summer and peaked in fall and winter. Overall, we saw little variability in transmission across different outbreaks settings in the United States. |
format | Online Article Text |
id | pubmed-7392428 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Centers for Disease Control and Prevention |
record_format | MEDLINE/PubMed |
spelling | pubmed-73924282020-08-06 Characterizing Norovirus Transmission from Outbreak Data, United States Steele, Molly K. Wikswo, Mary E. Hall, Aron J. Koelle, Katia Handel, Andreas Levy, Karen Waller, Lance A. Lopman, Ben A. Emerg Infect Dis Research Norovirus is the leading cause of acute gastroenteritis outbreaks in the United States. We estimated the basic (R(0)) and effective (R(e)) reproduction numbers for 7,094 norovirus outbreaks reported to the National Outbreak Reporting System (NORS) during 2009–2017 and used regression models to assess whether transmission varied by outbreak setting. The median R(0) was 2.75 (interquartile range [IQR] 2.38–3.65), and median R(e) was 1.29 (IQR 1.12–1.74). Long-term care and assisted living facilities had an R(0) of 3.35 (95% CI 3.26–3.45), but R(0) did not differ substantially for outbreaks in other settings, except for outbreaks in schools, colleges, and universities, which had an R(0) of 2.92 (95% CI 2.82–3.03). Seasonally, R(0) was lowest (3.11 [95% CI 2.97–3.25]) in summer and peaked in fall and winter. Overall, we saw little variability in transmission across different outbreaks settings in the United States. Centers for Disease Control and Prevention 2020-08 /pmc/articles/PMC7392428/ /pubmed/32687043 http://dx.doi.org/10.3201/eid2608.191537 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited. |
spellingShingle | Research Steele, Molly K. Wikswo, Mary E. Hall, Aron J. Koelle, Katia Handel, Andreas Levy, Karen Waller, Lance A. Lopman, Ben A. Characterizing Norovirus Transmission from Outbreak Data, United States |
title | Characterizing Norovirus Transmission from Outbreak Data, United States |
title_full | Characterizing Norovirus Transmission from Outbreak Data, United States |
title_fullStr | Characterizing Norovirus Transmission from Outbreak Data, United States |
title_full_unstemmed | Characterizing Norovirus Transmission from Outbreak Data, United States |
title_short | Characterizing Norovirus Transmission from Outbreak Data, United States |
title_sort | characterizing norovirus transmission from outbreak data, united states |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392428/ https://www.ncbi.nlm.nih.gov/pubmed/32687043 http://dx.doi.org/10.3201/eid2608.191537 |
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