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Tumor Targeting by α(v)β(3)-Integrin-Specific Lipid Nanoparticles Occurs via Phagocyte Hitchhiking
[Image: see text] Although the first nanomedicine was clinically approved more than two decades ago, nanoparticles’ (NP) in vivo behavior is complex and the immune system’s role in their application remains elusive. At present, only passive-targeting nanoformulations have been clinically approved, w...
Autores principales: | Sofias, Alexandros Marios, Toner, Yohana C., Meerwaldt, Anu E., van Leent, Mandy M. T., Soultanidis, Georgios, Elschot, Mattijs, Gonai, Haruki, Grendstad, Kristin, Flobak, Åsmund, Neckmann, Ulrike, Wolowczyk, Camilla, Fisher, Elizabeth L., Reiner, Thomas, Davies, Catharina de Lange, Bjørkøy, Geir, Teunissen, Abraham J. P., Ochando, Jordi, Pérez-Medina, Carlos, Mulder, Willem J. M., Hak, Sjoerd |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical Society
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392528/ https://www.ncbi.nlm.nih.gov/pubmed/32413260 http://dx.doi.org/10.1021/acsnano.9b08693 |
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