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High glucose levels increase influenza-associated damage to the pulmonary epithelial-endothelial barrier

Diabetes mellitus is a known susceptibility factor for severe influenza virus infections. However, the mechanisms that underlie this susceptibility remain incompletely understood. Here, the effects of high glucose levels on influenza severity were investigated using an in vitro model of the pulmonar...

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Detalles Bibliográficos
Autores principales: Hulme, Katina D, Yan, Limin, Marshall, Rebecca J, Bloxham, Conor J, Upton, Kyle R, Hasnain, Sumaira Z, Bielefeldt-Ohmann, Helle, Loh, Zhixuan, Ronacher, Katharina, Chew, Keng Yih, Gallo, Linda A, Short, Kirsty R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392605/
https://www.ncbi.nlm.nih.gov/pubmed/32697191
http://dx.doi.org/10.7554/eLife.56907