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The Future of Phage: Ethical Challenges of Using Phage Therapy to Treat Bacterial Infections
For over a century, scientists have run experiments using phage viruses to treat bacterial infections. Until recently, the results were inconclusive because the mechanisms viruses use to attack bacteria were poorly understood. With the development of molecular biology, scientists now have a better s...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Oxford University Press
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392637/ https://www.ncbi.nlm.nih.gov/pubmed/32760449 http://dx.doi.org/10.1093/phe/phaa003 |
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author | Anomaly, Jonathan |
author_facet | Anomaly, Jonathan |
author_sort | Anomaly, Jonathan |
collection | PubMed |
description | For over a century, scientists have run experiments using phage viruses to treat bacterial infections. Until recently, the results were inconclusive because the mechanisms viruses use to attack bacteria were poorly understood. With the development of molecular biology, scientists now have a better sense of how phage work, and how they can be used to target infections. As resistance to traditional antibiotics continues to spread around the world, there is a moral imperative to facilitate research into phage therapy as an alternative treatment. This essay reviews ethical questions raised by phage therapy, and discusses regulatory challenges associated with phage research, and phage treatments. |
format | Online Article Text |
id | pubmed-7392637 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-73926372020-08-04 The Future of Phage: Ethical Challenges of Using Phage Therapy to Treat Bacterial Infections Anomaly, Jonathan Public Health Ethics Original Articles For over a century, scientists have run experiments using phage viruses to treat bacterial infections. Until recently, the results were inconclusive because the mechanisms viruses use to attack bacteria were poorly understood. With the development of molecular biology, scientists now have a better sense of how phage work, and how they can be used to target infections. As resistance to traditional antibiotics continues to spread around the world, there is a moral imperative to facilitate research into phage therapy as an alternative treatment. This essay reviews ethical questions raised by phage therapy, and discusses regulatory challenges associated with phage research, and phage treatments. Oxford University Press 2020-02-20 /pmc/articles/PMC7392637/ /pubmed/32760449 http://dx.doi.org/10.1093/phe/phaa003 Text en © The Author(s) 2020. Published by Oxford University Press. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Original Articles Anomaly, Jonathan The Future of Phage: Ethical Challenges of Using Phage Therapy to Treat Bacterial Infections |
title | The Future of Phage: Ethical Challenges of Using Phage Therapy to Treat Bacterial Infections |
title_full | The Future of Phage: Ethical Challenges of Using Phage Therapy to Treat Bacterial Infections |
title_fullStr | The Future of Phage: Ethical Challenges of Using Phage Therapy to Treat Bacterial Infections |
title_full_unstemmed | The Future of Phage: Ethical Challenges of Using Phage Therapy to Treat Bacterial Infections |
title_short | The Future of Phage: Ethical Challenges of Using Phage Therapy to Treat Bacterial Infections |
title_sort | future of phage: ethical challenges of using phage therapy to treat bacterial infections |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392637/ https://www.ncbi.nlm.nih.gov/pubmed/32760449 http://dx.doi.org/10.1093/phe/phaa003 |
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