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The Future of Phage: Ethical Challenges of Using Phage Therapy to Treat Bacterial Infections

For over a century, scientists have run experiments using phage viruses to treat bacterial infections. Until recently, the results were inconclusive because the mechanisms viruses use to attack bacteria were poorly understood. With the development of molecular biology, scientists now have a better s...

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Detalles Bibliográficos
Autor principal: Anomaly, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392637/
https://www.ncbi.nlm.nih.gov/pubmed/32760449
http://dx.doi.org/10.1093/phe/phaa003
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description For over a century, scientists have run experiments using phage viruses to treat bacterial infections. Until recently, the results were inconclusive because the mechanisms viruses use to attack bacteria were poorly understood. With the development of molecular biology, scientists now have a better sense of how phage work, and how they can be used to target infections. As resistance to traditional antibiotics continues to spread around the world, there is a moral imperative to facilitate research into phage therapy as an alternative treatment. This essay reviews ethical questions raised by phage therapy, and discusses regulatory challenges associated with phage research, and phage treatments.
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spelling pubmed-73926372020-08-04 The Future of Phage: Ethical Challenges of Using Phage Therapy to Treat Bacterial Infections Anomaly, Jonathan Public Health Ethics Original Articles For over a century, scientists have run experiments using phage viruses to treat bacterial infections. Until recently, the results were inconclusive because the mechanisms viruses use to attack bacteria were poorly understood. With the development of molecular biology, scientists now have a better sense of how phage work, and how they can be used to target infections. As resistance to traditional antibiotics continues to spread around the world, there is a moral imperative to facilitate research into phage therapy as an alternative treatment. This essay reviews ethical questions raised by phage therapy, and discusses regulatory challenges associated with phage research, and phage treatments. Oxford University Press 2020-02-20 /pmc/articles/PMC7392637/ /pubmed/32760449 http://dx.doi.org/10.1093/phe/phaa003 Text en © The Author(s) 2020. Published by Oxford University Press. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Original Articles
Anomaly, Jonathan
The Future of Phage: Ethical Challenges of Using Phage Therapy to Treat Bacterial Infections
title The Future of Phage: Ethical Challenges of Using Phage Therapy to Treat Bacterial Infections
title_full The Future of Phage: Ethical Challenges of Using Phage Therapy to Treat Bacterial Infections
title_fullStr The Future of Phage: Ethical Challenges of Using Phage Therapy to Treat Bacterial Infections
title_full_unstemmed The Future of Phage: Ethical Challenges of Using Phage Therapy to Treat Bacterial Infections
title_short The Future of Phage: Ethical Challenges of Using Phage Therapy to Treat Bacterial Infections
title_sort future of phage: ethical challenges of using phage therapy to treat bacterial infections
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392637/
https://www.ncbi.nlm.nih.gov/pubmed/32760449
http://dx.doi.org/10.1093/phe/phaa003
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