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The length of ribosomal binding site spacer sequence controls the production yield for intracellular and secreted proteins by Bacillus subtilis

BACKGROUND: Bacillus subtilis is widely used for the industrial production of recombinant proteins, mainly due to its high secretion capacity, but higher production yields can be achieved only if bottlenecks are removed. To this end, a crucial process is translation initiation which takes place at t...

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Detalles Bibliográficos
Autores principales: Volkenborn, Kristina, Kuschmierz, Laura, Benz, Nuka, Lenz, Patrick, Knapp, Andreas, Jaeger, Karl-Erich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392706/
https://www.ncbi.nlm.nih.gov/pubmed/32727460
http://dx.doi.org/10.1186/s12934-020-01404-2