Cargando…

CGGBP1-regulated cytosine methylation at CTCF-binding motifs resists stochasticity

BACKGROUND: The human CGGBP1 binds to GC-rich regions and interspersed repeats, maintains homeostasis of stochastic cytosine methylation and determines DNA-binding of CTCF. Interdependence between regulation of cytosine methylation and CTCF occupancy by CGGBP1 remains unknown. RESULTS: By analyzing...

Descripción completa

Detalles Bibliográficos
Autores principales: Patel, Manthan, Patel, Divyesh, Datta, Subhamoy, Singh, Umashankar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392725/
https://www.ncbi.nlm.nih.gov/pubmed/32727353
http://dx.doi.org/10.1186/s12863-020-00894-8