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Hoxd10 Is Required Systemically for Secretory Activation in Lactation and Interacts Genetically with Hoxd9

Targeted disruption of the murine Hoxd10 gene (ΔHoxd10) leads to a high frequency of localized (gland-to-gland or regionally within a gland) lactation impairment in homozygous mutant mice as a single gene mutation. The effect of Hoxd10 disruption was enhanced by simultaneous disruption of Hoxd9 (ΔHo...

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Detalles Bibliográficos
Autores principales: Landua, John D., Moraes, Ricardo, Carpenter, Ellen M., Lewis, Michael T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392944/
https://www.ncbi.nlm.nih.gov/pubmed/32705545
http://dx.doi.org/10.1007/s10911-020-09454-3