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Proangiogenic Hypoxia-Mimicking Agents Attenuate Osteogenic Potential of Adipose Stem/Stromal Cells

BACKGROUND: Insufficient vascularization hampers bone tissue engineering strategies for reconstructing large bone defects. Delivery of prolyl-hydroxylase inhibitors (PHIs) is an interesting approach to upregulate vascular endothelial growth factor (VEGF) by mimicking hypoxic stabilization of hypoxia...

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Detalles Bibliográficos
Autores principales:	Abu-Shahba, Ahmed G., Gebraad, Arjen, Kaur, Sippy, Paananen, Riku O., Peltoniemi, Hilkka, Seppänen-Kaijansinkko, Riitta, Mannerström, Bettina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Singapore 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392999/ https://www.ncbi.nlm.nih.gov/pubmed/32449039 http://dx.doi.org/10.1007/s13770-020-00259-3

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