Functional fine-mapping of noncoding risk variants in amyotrophic lateral sclerosis utilizing convolutional neural network

Recent large-scale genome-wide association studies have identified common genetic variations that may contribute to the risk of amyotrophic lateral sclerosis (ALS). However, pinpointing the risk variants in noncoding regions and underlying biological mechanisms remains a major challenge. Here, we co...

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Detalles Bibliográficos
Autores principales: Yousefian-Jazi, Ali, Sung, Min Kyung, Lee, Taeyeop, Hong, Yoon-Ho, Choi, Jung Kyoon, Choi, Jinwook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393092/
https://www.ncbi.nlm.nih.gov/pubmed/32732921
http://dx.doi.org/10.1038/s41598-020-69790-6

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