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Paraventricular hypothalamus mediates diurnal rhythm of metabolism
Defective rhythmic metabolism is associated with high-fat high-caloric diet (HFD) feeding, ageing and obesity; however, the neural basis underlying HFD effects on diurnal metabolism remains elusive. Here we show that deletion of BMAL1, a core clock gene, in paraventricular hypothalamic (PVH) neurons...
Autores principales: | Kim, Eun Ran, Xu, Yuanzhong, Cassidy, Ryan M., Lu, Yungang, Yang, Yongjie, Tian, Jinbin, Li, De-Pei, Van Drunen, Rachel, Ribas-Latre, Aleix, Cai, Zhao-Lin, Xue, Mingshan, Arenkiel, Benjamin R., Eckel-Mahan, Kristin, Xu, Yong, Tong, Qingchun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393104/ https://www.ncbi.nlm.nih.gov/pubmed/32732906 http://dx.doi.org/10.1038/s41467-020-17578-7 |
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