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Association between DNA methylation levels in brain tissue and late-life depression in community-based participants

OBJECTIVE: Major depressive disorder (MDD) arises from a combination of genetic and environmental risk factors and DNA methylation is one of the molecular mechanisms through which these factors can manifest. However, little is known about the epigenetic signature of MDD in brain tissue. This study a...

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Detalles Bibliográficos
Autores principales: Hüls, Anke, Robins, Chloe, Conneely, Karen N., De Jager, Philip L., Bennett, David A., Epstein, Michael P., Wingo, Thomas S., Wingo, Aliza P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393126/
https://www.ncbi.nlm.nih.gov/pubmed/32733030
http://dx.doi.org/10.1038/s41398-020-00948-6