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Exploiting graphlet decomposition to explain the structure of complex networks: the GHuST framework

The characterization of topology is crucial in understanding network evolution and behavior. This paper presents an innovative approach, the GHuST framework to describe complex-network topology from graphlet decomposition. This new framework exploits the local information provided by graphlets to gi...

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Autores principales: Espejo, Rafael, Mestre, Guillermo, Postigo, Fernando, Lumbreras, Sara, Ramos, Andres, Huang, Tao, Bompard, Ettore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393148/
https://www.ncbi.nlm.nih.gov/pubmed/32732972
http://dx.doi.org/10.1038/s41598-020-69795-1
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author Espejo, Rafael
Mestre, Guillermo
Postigo, Fernando
Lumbreras, Sara
Ramos, Andres
Huang, Tao
Bompard, Ettore
author_facet Espejo, Rafael
Mestre, Guillermo
Postigo, Fernando
Lumbreras, Sara
Ramos, Andres
Huang, Tao
Bompard, Ettore
author_sort Espejo, Rafael
collection PubMed
description The characterization of topology is crucial in understanding network evolution and behavior. This paper presents an innovative approach, the GHuST framework to describe complex-network topology from graphlet decomposition. This new framework exploits the local information provided by graphlets to give a global explanation of network topology. The GHuST framework is comprised of 12 metrics that analyze how 2- and 3-node graphlets shape the structure of networks. The main strengths of the GHuST framework are enhanced topological description, size independence, and computational simplicity. It allows for straight comparison among different networks disregarding their size. It also reduces the complexity of graphlet counting, since it does not use 4- and 5-node graphlets. The application of the novel framework to a large set of networks shows that it can classify networks of distinct nature based on their topological properties. To ease network classification and enhance the graphical representation of them, we reduce the 12 dimensions to their main principal components. Furthermore, the 12 dimensions are easily interpretable. This enables the connection between complex-network analyses and diverse real applications.
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spelling pubmed-73931482020-08-03 Exploiting graphlet decomposition to explain the structure of complex networks: the GHuST framework Espejo, Rafael Mestre, Guillermo Postigo, Fernando Lumbreras, Sara Ramos, Andres Huang, Tao Bompard, Ettore Sci Rep Article The characterization of topology is crucial in understanding network evolution and behavior. This paper presents an innovative approach, the GHuST framework to describe complex-network topology from graphlet decomposition. This new framework exploits the local information provided by graphlets to give a global explanation of network topology. The GHuST framework is comprised of 12 metrics that analyze how 2- and 3-node graphlets shape the structure of networks. The main strengths of the GHuST framework are enhanced topological description, size independence, and computational simplicity. It allows for straight comparison among different networks disregarding their size. It also reduces the complexity of graphlet counting, since it does not use 4- and 5-node graphlets. The application of the novel framework to a large set of networks shows that it can classify networks of distinct nature based on their topological properties. To ease network classification and enhance the graphical representation of them, we reduce the 12 dimensions to their main principal components. Furthermore, the 12 dimensions are easily interpretable. This enables the connection between complex-network analyses and diverse real applications. Nature Publishing Group UK 2020-07-30 /pmc/articles/PMC7393148/ /pubmed/32732972 http://dx.doi.org/10.1038/s41598-020-69795-1 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Espejo, Rafael
Mestre, Guillermo
Postigo, Fernando
Lumbreras, Sara
Ramos, Andres
Huang, Tao
Bompard, Ettore
Exploiting graphlet decomposition to explain the structure of complex networks: the GHuST framework
title Exploiting graphlet decomposition to explain the structure of complex networks: the GHuST framework
title_full Exploiting graphlet decomposition to explain the structure of complex networks: the GHuST framework
title_fullStr Exploiting graphlet decomposition to explain the structure of complex networks: the GHuST framework
title_full_unstemmed Exploiting graphlet decomposition to explain the structure of complex networks: the GHuST framework
title_short Exploiting graphlet decomposition to explain the structure of complex networks: the GHuST framework
title_sort exploiting graphlet decomposition to explain the structure of complex networks: the ghust framework
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393148/
https://www.ncbi.nlm.nih.gov/pubmed/32732972
http://dx.doi.org/10.1038/s41598-020-69795-1
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