Cargando…

The Water Channel Aquaporin 8 is a Critical Regulator of Intestinal Fluid Homeostasis in Collagenous Colitis

BACKGROUND AND AIMS: Diarrhoea is a common, debilitating symptom of gastrointestinal disorders. Pathomechanisms probably involve defects in trans-epithelial water transport, but the role of aquaporin [AQP] family water channels in diarrhoea-predominant diseases is unknown. We investigated the involv...

Descripción completa

Detalles Bibliográficos
Autores principales:	Escudero-Hernández, Celia, Münch, Andreas, Østvik, Ann-Elisabet, Granlund, Atle van Beelen, Koch, Stefan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393183/ https://www.ncbi.nlm.nih.gov/pubmed/32016376 http://dx.doi.org/10.1093/ecco-jcc/jjaa020

Ejemplares similares

Transcriptomic Profiling of Collagenous Colitis Identifies Hallmarks of Nondestructive Inflammatory Bowel Disease
por: Escudero-Hernández, Celia, et al.
Publicado: (2021)

Mucosal and faecal neutrophil gelatinase-associated lipocalin as potential biomarkers for collagenous colitis
por: Bakke, Ingunn, et al.
Publicado: (2021)

Profound gene expression changes in the epithelial monolayer of active ulcerative colitis and Crohn’s disease
por: Sæterstad, Siri, et al.
Publicado: (2022)

Activation of REG family proteins in colitis
por: Granlund, Atle Vand Beelen, et al.
Publicado: (2011)

Intestinal Epithelial Cells Express Immunomodulatory ISG15 During Active Ulcerative Colitis and Crohn’s Disease
por: Østvik, Ann Elisabet, et al.
Publicado: (2020)

C-C Motif Ligand 20 (CCL20) and C-C Motif Chemokine Receptor 6 (CCR6) in Human Peripheral Blood Mononuclear Cells: Dysregulated in Ulcerative Colitis and a Potential Role for CCL20 in IL-1β Release
por: Skovdahl, Helene Kolstad, et al.
Publicado: (2018)

REG gene expression in inflamed and healthy colon mucosa explored by in situ hybridisation
por: van Beelen Granlund, Atle, et al.
Publicado: (2013)

Expression of neutrophil gelatinase-associated lipocalin (NGAL) in the gut in Crohn’s disease
por: Thorsvik, Silje, et al.
Publicado: (2018)

Expression of CCL20 and Its Corresponding Receptor CCR6 Is Enhanced in Active Inflammatory Bowel Disease, and TLR3 Mediates CCL20 Expression in Colonic Epithelial Cells
por: Skovdahl, Helene Kolstad, et al.
Publicado: (2015)

Tofacitinib Downregulates TNF and Poly(I:C)-Dependent MHC-II Expression in the Colonic Epithelium
por: Gopalakrishnan, Shreya, et al.
Publicado: (2022)

Whole Genome Gene Expression Meta-Analysis of Inflammatory Bowel Disease Colon Mucosa Demonstrates Lack of Major Differences between Crohn's Disease and Ulcerative Colitis
por: Granlund, Atle van Beelen, et al.
Publicado: (2013)

Host–Viral Interactions in the Pathogenesis of Ulcerative Colitis
por: Bruland, Torunn, et al.
Publicado: (2021)

Cellular Distribution of Brain Aquaporins and Their Contribution to Cerebrospinal Fluid Homeostasis and Hydrocephalus
por: Trillo-Contreras, José Luis, et al.
Publicado: (2022)

Ulcer‐associated cell lineage expresses genes involved in regeneration and is hallmarked by high neutrophil gelatinase‐associated lipocalin (NGAL) levels
por: Thorsvik, Silje, et al.
Publicado: (2019)

Cancer Risk in Collagenous Colitis
por: Larsson, Johanna K., et al.
Publicado: (2019)

Intestinal fluid absorption in anadromous salmonids: importance of tight junctions and aquaporins
por: Sundell, Kristina S., et al.
Publicado: (2012)

Lack of effect of methotrexate in budesonide-refractory collagenous colitis
por: Münch, Andreas, et al.
Publicado: (2013)

A critical role of endothelial cell protein C receptor in the intestinal homeostasis in experimental colitis
por: Kondreddy, Vijay, et al.
Publicado: (2020)

The Role of Aquaporins in Ocular Lens Homeostasis
por: Schey, Kevin L., et al.
Publicado: (2017)

Nutritional Ketosis, Aquaporins, and Energy Homeostasis
por: Castro, Rita, et al.
Publicado: (2022)

Relevance of TNBS-Colitis in Rats: A Methodological Study with Endoscopic, Histologic and Transcriptomic Characterization and Correlation to IBD
por: Brenna, Øystein, et al.
Publicado: (2013)

Mucosal 5‐aminosalicylic acid concentration, drug formulation and mucosal microbiome in patients with quiescent ulcerative colitis
por: Olaisen, Maya, et al.
Publicado: (2019)

Correction: Relevance of TNBS-Colitis in Rats: A Methodological Study with Endoscopic, Histologic and Transcriptomic Characterization and Correlation to IBD
por: Brenna, Øystein, et al.
Publicado: (2013)

Implication of Porphyromonas gingivalis in colitis and homeostasis of intestinal epithelium
por: Seo, Yoojin, et al.
Publicado: (2019)

Fecal Fungal Microbiota (Mycobiome) Study as a Potential Tool for Precision Medicine in Inflammatory Bowel Disease
por: Balderramo, Domingo C., et al.
Publicado: (2023)

Expression, Distribution and Role of Aquaporin Water Channels in Human and Animal Stomach and Intestines
por: Zhu, Cui, et al.
Publicado: (2016)

Collagenous colitis associated with novel sprue-like intestinal diseases
por: Freeman, Hugh J.
Publicado: (2023)

Aquaporins: The renal water channels
por: Agarwal, S. K., et al.
Publicado: (2008)

Role of Aquaporin Water Channels in Airway Fluid Transport, Humidification, and Surface Liquid Hydration
por: Song, Yuanlin, et al.
Publicado: (2001)

Compartmentalization of Aquaporins in the Human Intestine
por: Cohly, Hari H. P., et al.
Publicado: (2008)

Vasoactive Intestinal Polypeptide Promotes Intestinal Barrier Homeostasis and Protection Against Colitis in Mice
por: Wu, Xiujuan, et al.
Publicado: (2015)

Aquaporin water channels in exocrine glands.
por: Steward, M, et al.
Publicado: (2000)

Aquaporin Channels in the Heart—Physiology and Pathophysiology
por: Verkerk, Arie O., et al.
Publicado: (2019)

Inhibitors of Mammalian Aquaporin Water Channels
por: Abir-Awan, Mohammed, et al.
Publicado: (2019)

The aquaporin family of membrane water channels
por: Engel, Andreas, et al.
Publicado: (1994)

Collagenous Colitis and Spondylarthropathy
por: Ben Abdelghani, Kaouther, et al.
Publicado: (2012)

An innately dangerous balancing act: intestinal homeostasis, inflammation, and colitis-associated cancer
por: Asquith, Mark, et al.
Publicado: (2010)

The Aquaporin Channel Repertoire of the Tardigrade Milnesium tardigradum
por: Grohme, Markus A., et al.
Publicado: (2013)

Structural Determinants of Oligomerization of the Aquaporin-4 Channel
por: Kitchen, Philip, et al.
Publicado: (2016)

Protein kinase CK2 is a critical regulator of epithelial homeostasis in chronic intestinal inflammation
por: Koch, Stefan, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_rjdtobkq93bvakr7bktrikkmvr