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The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research
Reproducible science requires transparent reporting. The ARRIVE guidelines (Animal Research: Reporting of In Vivo Experiments) were originally developed in 2010 to improve the reporting of animal research. They consist of a checklist of information to include in publications describing in vivo exper...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393194/ https://www.ncbi.nlm.nih.gov/pubmed/32662519 http://dx.doi.org/10.1111/bph.15193 |
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author | Percie du Sert, Nathalie Hurst, Viki Ahluwalia, Amrita Alam, Sabina Avey, Marc T. Baker, Monya Browne, William J. Clark, Alejandra Cuthill, Innes C. Dirnagl, Ulrich Emerson, Michael Garner, Paul Holgate, Stephen T. Howells, David W. Karp, Natasha A. Lazic, Stanley E. Lidster, Katie MacCallum, Catriona J. Macleod, Malcolm Pearl, Esther J. Petersen, Ole H. Rawle, Frances Reynolds, Penny Rooney, Kieron Sena, Emily S. Silberberg, Shai D. Steckler, Thomas Würbel, Hanno |
author_facet | Percie du Sert, Nathalie Hurst, Viki Ahluwalia, Amrita Alam, Sabina Avey, Marc T. Baker, Monya Browne, William J. Clark, Alejandra Cuthill, Innes C. Dirnagl, Ulrich Emerson, Michael Garner, Paul Holgate, Stephen T. Howells, David W. Karp, Natasha A. Lazic, Stanley E. Lidster, Katie MacCallum, Catriona J. Macleod, Malcolm Pearl, Esther J. Petersen, Ole H. Rawle, Frances Reynolds, Penny Rooney, Kieron Sena, Emily S. Silberberg, Shai D. Steckler, Thomas Würbel, Hanno |
author_sort | Percie du Sert, Nathalie |
collection | PubMed |
description | Reproducible science requires transparent reporting. The ARRIVE guidelines (Animal Research: Reporting of In Vivo Experiments) were originally developed in 2010 to improve the reporting of animal research. They consist of a checklist of information to include in publications describing in vivo experiments to enable others to scrutinise the work adequately, evaluate its methodological rigour, and reproduce the methods and results. Despite considerable levels of endorsement by funders and journals over the years, adherence to the guidelines has been inconsistent, and the anticipated improvements in the quality of reporting in animal research publications have not been achieved. Here, we introduce ARRIVE 2.0. The guidelines have been updated and information reorganised to facilitate their use in practice. We used a Delphi exercise to prioritise and divide the items of the guidelines into 2 sets, the “ARRIVE Essential 10,” which constitutes the minimum requirement, and the “Recommended Set,” which describes the research context. This division facilitates improved reporting of animal research by supporting a stepwise approach to implementation. This helps journal editors and reviewers verify that the most important items are being reported in manuscripts. We have also developed the accompanying Explanation and Elaboration (E&E) document, which serves (1) to explain the rationale behind each item in the guidelines, (2) to clarify key concepts, and (3) to provide illustrative examples. We aim, through these changes, to help ensure that researchers, reviewers, and journal editors are better equipped to improve the rigour and transparency of the scientific process and thus reproducibility. |
format | Online Article Text |
id | pubmed-7393194 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-73931942020-08-04 The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research Percie du Sert, Nathalie Hurst, Viki Ahluwalia, Amrita Alam, Sabina Avey, Marc T. Baker, Monya Browne, William J. Clark, Alejandra Cuthill, Innes C. Dirnagl, Ulrich Emerson, Michael Garner, Paul Holgate, Stephen T. Howells, David W. Karp, Natasha A. Lazic, Stanley E. Lidster, Katie MacCallum, Catriona J. Macleod, Malcolm Pearl, Esther J. Petersen, Ole H. Rawle, Frances Reynolds, Penny Rooney, Kieron Sena, Emily S. Silberberg, Shai D. Steckler, Thomas Würbel, Hanno Br J Pharmacol Perspective Reproducible science requires transparent reporting. The ARRIVE guidelines (Animal Research: Reporting of In Vivo Experiments) were originally developed in 2010 to improve the reporting of animal research. They consist of a checklist of information to include in publications describing in vivo experiments to enable others to scrutinise the work adequately, evaluate its methodological rigour, and reproduce the methods and results. Despite considerable levels of endorsement by funders and journals over the years, adherence to the guidelines has been inconsistent, and the anticipated improvements in the quality of reporting in animal research publications have not been achieved. Here, we introduce ARRIVE 2.0. The guidelines have been updated and information reorganised to facilitate their use in practice. We used a Delphi exercise to prioritise and divide the items of the guidelines into 2 sets, the “ARRIVE Essential 10,” which constitutes the minimum requirement, and the “Recommended Set,” which describes the research context. This division facilitates improved reporting of animal research by supporting a stepwise approach to implementation. This helps journal editors and reviewers verify that the most important items are being reported in manuscripts. We have also developed the accompanying Explanation and Elaboration (E&E) document, which serves (1) to explain the rationale behind each item in the guidelines, (2) to clarify key concepts, and (3) to provide illustrative examples. We aim, through these changes, to help ensure that researchers, reviewers, and journal editors are better equipped to improve the rigour and transparency of the scientific process and thus reproducibility. John Wiley and Sons Inc. 2020-07-14 2020-08 /pmc/articles/PMC7393194/ /pubmed/32662519 http://dx.doi.org/10.1111/bph.15193 Text en © 2020 The Authors. British Journal of Pharmacology published by John Wiley & Sons Ltd on behalf of British Pharmacological Society This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Perspective Percie du Sert, Nathalie Hurst, Viki Ahluwalia, Amrita Alam, Sabina Avey, Marc T. Baker, Monya Browne, William J. Clark, Alejandra Cuthill, Innes C. Dirnagl, Ulrich Emerson, Michael Garner, Paul Holgate, Stephen T. Howells, David W. Karp, Natasha A. Lazic, Stanley E. Lidster, Katie MacCallum, Catriona J. Macleod, Malcolm Pearl, Esther J. Petersen, Ole H. Rawle, Frances Reynolds, Penny Rooney, Kieron Sena, Emily S. Silberberg, Shai D. Steckler, Thomas Würbel, Hanno The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research |
title | The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research |
title_full | The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research |
title_fullStr | The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research |
title_full_unstemmed | The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research |
title_short | The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research |
title_sort | arrive guidelines 2.0: updated guidelines for reporting animal research |
topic | Perspective |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393194/ https://www.ncbi.nlm.nih.gov/pubmed/32662519 http://dx.doi.org/10.1111/bph.15193 |
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