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Inhibition of Sonic Hedgehog Signaling Suppresses Glioma Stem-Like Cells Likely Through Inducing Autophagic Cell Death
Glioblastoma (GBM) often recurs after radio- and chemotherapies leading to poor prognosis. Glioma stem-like cells (GSCs) contribute to drug resistance and recurrence. Thus, understanding cellular mechanism underlying the growth of GSCs is critical for the treatment of GBM. Here GSCs were isolated fr...
Autores principales: | Hung, Hui-Chi, Liu, Chan-Chuan, Chuang, Jian-Ying, Su, Chun-Lin, Gean, Po-Wu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393230/ https://www.ncbi.nlm.nih.gov/pubmed/32793494 http://dx.doi.org/10.3389/fonc.2020.01233 |
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