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ACCORD: A Multicentre, Seamless, Phase 2 Adaptive Randomisation Platform Study to Assess the Efficacy and Safety of Multiple Candidate Agents for the Treatment of COVID-19 in Hospitalised Patients: A structured summary of a study protocol for a randomised controlled trial
OBJECTIVES: Stage 1: To evaluate the safety and efficacy of candidate agents as add-on therapies to standard of care (SoC) in patients hospitalised with COVID-19 in a screening stage. Stage 2: To confirm the efficacy of candidate agents selected on the basis of evidence from Stage 1 in patients hosp...
Autores principales: | Wilkinson, Tom, Dixon, Rupert, Page, Clive, Carroll, Miles, Griffiths, Gareth, Ho, Ling-Pei, De Soyza, Anthony, Felton, Timothy, Lewis, Keir E., Phekoo, Karen, Chalmers, James D., Gordon, Anthony, McGarvey, Lorcan, Doherty, Jillian, Read, Robert C., Shankar-Hari, Manu, Martinez-Alier, Nuria, O’Kelly, Michael, Duncan, Graeme, Walles, Roelize, Sykes, James, Summers, Charlotte, Singh, Dave |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393340/ https://www.ncbi.nlm.nih.gov/pubmed/32736596 http://dx.doi.org/10.1186/s13063-020-04584-9 |
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