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Efficacy of a Novel Mitochondrial-Derived Peptide in a Porcine Model of Myocardial Ischemia/Reperfusion Injury

With the complexities that surround myocardial ischemia/reperfusion (MI/R) injury, therapies adjunctive to reperfusion that elicit beneficial pleiotropic effects and do not overlap with standard of care are necessary. This study found that the mitochondrial-derived peptide S14G-humanin (HNG) (2 mg/k...

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Detalles Bibliográficos
Autores principales: Sharp, Thomas E., Gong, Zhenwei, Scarborough, Amy, Goetzman, Eric S., Ali, Murtuza J., Spaletra, Pablo, Lefer, David J., Muzumdar, Radhika H., Goodchild, Traci T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393416/
https://www.ncbi.nlm.nih.gov/pubmed/32760857
http://dx.doi.org/10.1016/j.jacbts.2020.04.015