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Well-balanced immune response and protective efficacy induced by a single dose of live attenuated tetravalent dengue vaccine (KD-382) in monkeys

One of the challenges developing a live attenuated tetravalent dengue vaccine (TDV) is to overcome the presumed viral interference that may be preventing the induction of a balanced immune response to all 4 serotypes of the dengue virus (DENV1–4). Our live attenuated TDV candidate was developed from...

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Detalles Bibliográficos
Autores principales:	Yoshimura, Masaya, Shinmura, Yasuhiko, Takagi, Shota, Kameyama, Kazuhisa, Sonoda, Kengo, Koide, Fusataka, Yoksan, Sutee, Kimachi, Kazuhiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393427/ https://www.ncbi.nlm.nih.gov/pubmed/32760828 http://dx.doi.org/10.1016/j.heliyon.2020.e04506

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