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A Giant Childhood Mesenteric Lipoblastoma With Extensive Maturation

Abdominal lipoblastomas are uncommon soft tissue tumors in children and rarely arise from the mesentery. Due to intraabdominal location and slow growth, these masses can go unnoticed for long periods of time and often found on surgical exploration. We present a case of a 12-year-old male with years...

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Autores principales: Squillaro, Anthony I., Chow, Monica D., Arias, Fernando, Sadimin, Evita T., Lee, Yi-Horng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393439/
https://www.ncbi.nlm.nih.gov/pubmed/32793530
http://dx.doi.org/10.3389/fped.2020.00404
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author Squillaro, Anthony I.
Chow, Monica D.
Arias, Fernando
Sadimin, Evita T.
Lee, Yi-Horng
author_facet Squillaro, Anthony I.
Chow, Monica D.
Arias, Fernando
Sadimin, Evita T.
Lee, Yi-Horng
author_sort Squillaro, Anthony I.
collection PubMed
description Abdominal lipoblastomas are uncommon soft tissue tumors in children and rarely arise from the mesentery. Due to intraabdominal location and slow growth, these masses can go unnoticed for long periods of time and often found on surgical exploration. We present a case of a 12-year-old male with years of abdominal distension accompanied by new onset early satiety that was found to have an intra-abdominal mass. He underwent an exploratory laparotomy revealing a large 33 x 27 x 15 cm rubbery mesenteric mass displacing the entire intra-abdominal contents, connected by a single vascular pedicle and encasing a loop of small intestine. The mass was resected and the patient did well without signs of recurrence. Histology confirmed the presence of mature adipocytes but on further cytogenetic analysis, a translocation between chromosomes 2 and 8 at the 12q arm was detected, which is often associated with lipoblastomas. This case represents the one of the largest mesenteric lipoblastomas that matured extensively to lipoma-like histology at the time of surgical resection.
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spelling pubmed-73934392020-08-12 A Giant Childhood Mesenteric Lipoblastoma With Extensive Maturation Squillaro, Anthony I. Chow, Monica D. Arias, Fernando Sadimin, Evita T. Lee, Yi-Horng Front Pediatr Pediatrics Abdominal lipoblastomas are uncommon soft tissue tumors in children and rarely arise from the mesentery. Due to intraabdominal location and slow growth, these masses can go unnoticed for long periods of time and often found on surgical exploration. We present a case of a 12-year-old male with years of abdominal distension accompanied by new onset early satiety that was found to have an intra-abdominal mass. He underwent an exploratory laparotomy revealing a large 33 x 27 x 15 cm rubbery mesenteric mass displacing the entire intra-abdominal contents, connected by a single vascular pedicle and encasing a loop of small intestine. The mass was resected and the patient did well without signs of recurrence. Histology confirmed the presence of mature adipocytes but on further cytogenetic analysis, a translocation between chromosomes 2 and 8 at the 12q arm was detected, which is often associated with lipoblastomas. This case represents the one of the largest mesenteric lipoblastomas that matured extensively to lipoma-like histology at the time of surgical resection. Frontiers Media S.A. 2020-07-24 /pmc/articles/PMC7393439/ /pubmed/32793530 http://dx.doi.org/10.3389/fped.2020.00404 Text en Copyright © 2020 Squillaro, Chow, Arias, Sadimin and Lee. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pediatrics
Squillaro, Anthony I.
Chow, Monica D.
Arias, Fernando
Sadimin, Evita T.
Lee, Yi-Horng
A Giant Childhood Mesenteric Lipoblastoma With Extensive Maturation
title A Giant Childhood Mesenteric Lipoblastoma With Extensive Maturation
title_full A Giant Childhood Mesenteric Lipoblastoma With Extensive Maturation
title_fullStr A Giant Childhood Mesenteric Lipoblastoma With Extensive Maturation
title_full_unstemmed A Giant Childhood Mesenteric Lipoblastoma With Extensive Maturation
title_short A Giant Childhood Mesenteric Lipoblastoma With Extensive Maturation
title_sort giant childhood mesenteric lipoblastoma with extensive maturation
topic Pediatrics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393439/
https://www.ncbi.nlm.nih.gov/pubmed/32793530
http://dx.doi.org/10.3389/fped.2020.00404
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