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A Giant Childhood Mesenteric Lipoblastoma With Extensive Maturation
Abdominal lipoblastomas are uncommon soft tissue tumors in children and rarely arise from the mesentery. Due to intraabdominal location and slow growth, these masses can go unnoticed for long periods of time and often found on surgical exploration. We present a case of a 12-year-old male with years...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393439/ https://www.ncbi.nlm.nih.gov/pubmed/32793530 http://dx.doi.org/10.3389/fped.2020.00404 |
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author | Squillaro, Anthony I. Chow, Monica D. Arias, Fernando Sadimin, Evita T. Lee, Yi-Horng |
author_facet | Squillaro, Anthony I. Chow, Monica D. Arias, Fernando Sadimin, Evita T. Lee, Yi-Horng |
author_sort | Squillaro, Anthony I. |
collection | PubMed |
description | Abdominal lipoblastomas are uncommon soft tissue tumors in children and rarely arise from the mesentery. Due to intraabdominal location and slow growth, these masses can go unnoticed for long periods of time and often found on surgical exploration. We present a case of a 12-year-old male with years of abdominal distension accompanied by new onset early satiety that was found to have an intra-abdominal mass. He underwent an exploratory laparotomy revealing a large 33 x 27 x 15 cm rubbery mesenteric mass displacing the entire intra-abdominal contents, connected by a single vascular pedicle and encasing a loop of small intestine. The mass was resected and the patient did well without signs of recurrence. Histology confirmed the presence of mature adipocytes but on further cytogenetic analysis, a translocation between chromosomes 2 and 8 at the 12q arm was detected, which is often associated with lipoblastomas. This case represents the one of the largest mesenteric lipoblastomas that matured extensively to lipoma-like histology at the time of surgical resection. |
format | Online Article Text |
id | pubmed-7393439 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-73934392020-08-12 A Giant Childhood Mesenteric Lipoblastoma With Extensive Maturation Squillaro, Anthony I. Chow, Monica D. Arias, Fernando Sadimin, Evita T. Lee, Yi-Horng Front Pediatr Pediatrics Abdominal lipoblastomas are uncommon soft tissue tumors in children and rarely arise from the mesentery. Due to intraabdominal location and slow growth, these masses can go unnoticed for long periods of time and often found on surgical exploration. We present a case of a 12-year-old male with years of abdominal distension accompanied by new onset early satiety that was found to have an intra-abdominal mass. He underwent an exploratory laparotomy revealing a large 33 x 27 x 15 cm rubbery mesenteric mass displacing the entire intra-abdominal contents, connected by a single vascular pedicle and encasing a loop of small intestine. The mass was resected and the patient did well without signs of recurrence. Histology confirmed the presence of mature adipocytes but on further cytogenetic analysis, a translocation between chromosomes 2 and 8 at the 12q arm was detected, which is often associated with lipoblastomas. This case represents the one of the largest mesenteric lipoblastomas that matured extensively to lipoma-like histology at the time of surgical resection. Frontiers Media S.A. 2020-07-24 /pmc/articles/PMC7393439/ /pubmed/32793530 http://dx.doi.org/10.3389/fped.2020.00404 Text en Copyright © 2020 Squillaro, Chow, Arias, Sadimin and Lee. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Pediatrics Squillaro, Anthony I. Chow, Monica D. Arias, Fernando Sadimin, Evita T. Lee, Yi-Horng A Giant Childhood Mesenteric Lipoblastoma With Extensive Maturation |
title | A Giant Childhood Mesenteric Lipoblastoma With Extensive Maturation |
title_full | A Giant Childhood Mesenteric Lipoblastoma With Extensive Maturation |
title_fullStr | A Giant Childhood Mesenteric Lipoblastoma With Extensive Maturation |
title_full_unstemmed | A Giant Childhood Mesenteric Lipoblastoma With Extensive Maturation |
title_short | A Giant Childhood Mesenteric Lipoblastoma With Extensive Maturation |
title_sort | giant childhood mesenteric lipoblastoma with extensive maturation |
topic | Pediatrics |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393439/ https://www.ncbi.nlm.nih.gov/pubmed/32793530 http://dx.doi.org/10.3389/fped.2020.00404 |
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