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Stroke care and outcomes in the Department of Neurology in Parakou, Benin: Retrospective cohort study

INTRODUCTION: Stroke is one of the most common causes of high mortality rates in Africa with many unknown aspects around its prognosis. In this study we aim to describe stroke characteristics and in-hospital mortality of stroke in Parakou. METHODS: This is a retrospective cohort study including all...

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Autores principales: Adoukonou, Thierry, Agbétou, Mendinatou, Sowanou, Arlos, Kossi, Oyéné, Fotso, Pervenche, Houéhanou, Corine, Vallat, Jean-Michel, Houinato, Dismand, Preux, Pierre-Marie, Lacroix, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393444/
https://www.ncbi.nlm.nih.gov/pubmed/32760584
http://dx.doi.org/10.1016/j.amsu.2020.07.041
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author Adoukonou, Thierry
Agbétou, Mendinatou
Sowanou, Arlos
Kossi, Oyéné
Fotso, Pervenche
Houéhanou, Corine
Vallat, Jean-Michel
Houinato, Dismand
Preux, Pierre-Marie
Lacroix, Philippe
author_facet Adoukonou, Thierry
Agbétou, Mendinatou
Sowanou, Arlos
Kossi, Oyéné
Fotso, Pervenche
Houéhanou, Corine
Vallat, Jean-Michel
Houinato, Dismand
Preux, Pierre-Marie
Lacroix, Philippe
author_sort Adoukonou, Thierry
collection PubMed
description INTRODUCTION: Stroke is one of the most common causes of high mortality rates in Africa with many unknown aspects around its prognosis. In this study we aim to describe stroke characteristics and in-hospital mortality of stroke in Parakou. METHODS: This is a retrospective cohort study including all stroke patients admitted to the Department of Neurology at Parakou Teaching Hospital from January 1, 2013 through to December 31, 2019. Clinical data, vascular risk factors, stroke subtype and outcome data were recorded. The in-hospital case-fatality and its associated factors were determined. The study was approved by the Local Ethics Committee of Biomedical research and has been registered under the unique indentifying number researchregistry5687 and is available at https://www.researchregistry.com/browse-the-registry#home/ RESULTS: Stroke cases represented 51.5% of all patients. There were 372 patients included in the study with a mean age of 58.2 ± 14.2 years. The sex ratio was 1:3. Ischemic stroke accounted for 40.3%, intracerebral hemorrhage 30.4%, and unknown 29.3%. The main vascular risk factors were hypertension (69.1%), alcoholism (23.9%) and diabetes mellitus (16.9%). The mean NIHSS at admission was 9.4 ± 5.7 and the length of hospital stay was 9.0 ± 7.3. The most common complications recorded during the acute phase were swallowing disorders (10.2%), pneumonia (9.1%) and urinary tract infections (8.3%). The in-hospital case fatality was 6.2% and was associated with loss of consciousness (p = 0.0001), high NIHSS on admission (p = 0.001), fever (p = 0.0001), swallowing disorders (p = 0.001) and leukocytosis (p = 0.021). On discharge, 27.6% were independent and 97.8% were on antihypertensive drugs. CONCLUSION: The in-hospital stroke mortality was close to that reported by other studies in Africa.
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spelling pubmed-73934442020-08-04 Stroke care and outcomes in the Department of Neurology in Parakou, Benin: Retrospective cohort study Adoukonou, Thierry Agbétou, Mendinatou Sowanou, Arlos Kossi, Oyéné Fotso, Pervenche Houéhanou, Corine Vallat, Jean-Michel Houinato, Dismand Preux, Pierre-Marie Lacroix, Philippe Ann Med Surg (Lond) Original Research INTRODUCTION: Stroke is one of the most common causes of high mortality rates in Africa with many unknown aspects around its prognosis. In this study we aim to describe stroke characteristics and in-hospital mortality of stroke in Parakou. METHODS: This is a retrospective cohort study including all stroke patients admitted to the Department of Neurology at Parakou Teaching Hospital from January 1, 2013 through to December 31, 2019. Clinical data, vascular risk factors, stroke subtype and outcome data were recorded. The in-hospital case-fatality and its associated factors were determined. The study was approved by the Local Ethics Committee of Biomedical research and has been registered under the unique indentifying number researchregistry5687 and is available at https://www.researchregistry.com/browse-the-registry#home/ RESULTS: Stroke cases represented 51.5% of all patients. There were 372 patients included in the study with a mean age of 58.2 ± 14.2 years. The sex ratio was 1:3. Ischemic stroke accounted for 40.3%, intracerebral hemorrhage 30.4%, and unknown 29.3%. The main vascular risk factors were hypertension (69.1%), alcoholism (23.9%) and diabetes mellitus (16.9%). The mean NIHSS at admission was 9.4 ± 5.7 and the length of hospital stay was 9.0 ± 7.3. The most common complications recorded during the acute phase were swallowing disorders (10.2%), pneumonia (9.1%) and urinary tract infections (8.3%). The in-hospital case fatality was 6.2% and was associated with loss of consciousness (p = 0.0001), high NIHSS on admission (p = 0.001), fever (p = 0.0001), swallowing disorders (p = 0.001) and leukocytosis (p = 0.021). On discharge, 27.6% were independent and 97.8% were on antihypertensive drugs. CONCLUSION: The in-hospital stroke mortality was close to that reported by other studies in Africa. Elsevier 2020-07-28 /pmc/articles/PMC7393444/ /pubmed/32760584 http://dx.doi.org/10.1016/j.amsu.2020.07.041 Text en © 2020 The Author(s) http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Original Research
Adoukonou, Thierry
Agbétou, Mendinatou
Sowanou, Arlos
Kossi, Oyéné
Fotso, Pervenche
Houéhanou, Corine
Vallat, Jean-Michel
Houinato, Dismand
Preux, Pierre-Marie
Lacroix, Philippe
Stroke care and outcomes in the Department of Neurology in Parakou, Benin: Retrospective cohort study
title Stroke care and outcomes in the Department of Neurology in Parakou, Benin: Retrospective cohort study
title_full Stroke care and outcomes in the Department of Neurology in Parakou, Benin: Retrospective cohort study
title_fullStr Stroke care and outcomes in the Department of Neurology in Parakou, Benin: Retrospective cohort study
title_full_unstemmed Stroke care and outcomes in the Department of Neurology in Parakou, Benin: Retrospective cohort study
title_short Stroke care and outcomes in the Department of Neurology in Parakou, Benin: Retrospective cohort study
title_sort stroke care and outcomes in the department of neurology in parakou, benin: retrospective cohort study
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393444/
https://www.ncbi.nlm.nih.gov/pubmed/32760584
http://dx.doi.org/10.1016/j.amsu.2020.07.041
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