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TP53 mutational landscape of metastatic head and neck cancer reveals patterns of mutation selection
BACKGROUND: Head and neck squamous cell carcinoma is a heterogeneous disease with respect to the anatomic site of the primary tumor. On the other hand, it is highly recurrent, and once metastatic, it is associated with poor prognosis. TP53 is the most commonly mutated gene in primary disease. TP53 m...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393519/ https://www.ncbi.nlm.nih.gov/pubmed/32739866 http://dx.doi.org/10.1016/j.ebiom.2020.102905 |