CAR-T design: Elements and their synergistic function

Chimeric antigen receptor (CAR) T cells use re-engineered cell surface receptors to specifically bind to and lyse oncogenic cells. Two clinically approved CAR-T–cell therapies have significant clinical efficacy in treating CD19-positive B cell cancers. With widespread interest to deploy this immunot...

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Detalles Bibliográficos
Autores principales: Jayaraman, Jayapriya, Mellody, Michael P., Hou, Andrew J., Desai, Ruchi P., Fung, Audrey W., Pham, An Huynh Thuy, Chen, Yvonne Y., Zhao, Weian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393540/
https://www.ncbi.nlm.nih.gov/pubmed/32739874
http://dx.doi.org/10.1016/j.ebiom.2020.102931

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393540/
https://www.ncbi.nlm.nih.gov/pubmed/32739874
http://dx.doi.org/10.1016/j.ebiom.2020.102931

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