Cargando…

CAR-T design: Elements and their synergistic function

Chimeric antigen receptor (CAR) T cells use re-engineered cell surface receptors to specifically bind to and lyse oncogenic cells. Two clinically approved CAR-T–cell therapies have significant clinical efficacy in treating CD19-positive B cell cancers. With widespread interest to deploy this immunot...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jayaraman, Jayapriya, Mellody, Michael P., Hou, Andrew J., Desai, Ruchi P., Fung, Audrey W., Pham, An Huynh Thuy, Chen, Yvonne Y., Zhao, Weian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393540/ https://www.ncbi.nlm.nih.gov/pubmed/32739874 http://dx.doi.org/10.1016/j.ebiom.2020.102931

Ejemplares similares

A high throughput bispecific antibody discovery pipeline
por: Segaliny, Aude I., et al.
Publicado: (2023)

CAR-Macrophages and CAR-T Cells Synergistically Kill Tumor Cells In Vitro
por: Liu, Maoxuan, et al.
Publicado: (2022)

Acoustic Radiation Force Impulse Imaging in Benign and Malignant Breast Lesions
por: Jayaraman, Jayapriya, et al.
Publicado: (2017)

The development of CAR design for tumor CAR-T cell therapy
por: Xu, Dandan, et al.
Publicado: (2018)

Incorporation of functional elements enhances the antitumor capacity of CAR T cells
por: Qin, Le, et al.
Publicado: (2017)

Making Potent CAR T Cells Using Genetic Engineering and Synergistic Agents
por: Park, Chi Hoon
Publicado: (2021)

PASCAR: a multiscale framework to explore the design space of constitutive and inducible CAR T cells
por: Rajakaruna, Harshana, et al.
Publicado: (2023)

TGF‐β–responsive CAR‐T cells promote anti‐tumor immune function
por: Hou, Andrew J., et al.
Publicado: (2018)

CAR T Cells: A Snapshot on the Growing Options to Design a CAR
por: Holzinger, Astrid, et al.
Publicado: (2019)

Steatosis and Metabolic Disorders Associated with Synergistic Activation of the CAR/RXR Heterodimer by Pesticides
por: Dauwe, Yannick, et al.
Publicado: (2023)

Selective cytotoxicity of a Vietnamese traditional formula, Nam Dia long, against MCF-7 cells by synergistic effects
por: Nguyen, My-Nuong Thi, et al.
Publicado: (2016)

The carP lncRNA Is a carS-Related Regulatory Element with Broad Effects on the Fusarium fujikuroi Transcriptome
por: Pardo-Medina, Javier, et al.
Publicado: (2021)

Synergistic apoptosis of human gastric cancer cells by bortezomib and TRAIL
por: Bui, Hang Thi Thuy, et al.
Publicado: (2019)

La codependencia : qué es, de dónde procede, cómo sabotea nuestras vidas : aprende a hacerle frente /
por: Mellody, Pia
Publicado: (2005)

Sentirse libre es ser feliz : cómo vencer las dependencias y recuperar la autoestima
por: Mellody, Pia
Publicado: (1994)

Application and Design of Switches Used in CAR
por: Głowacki, Paweł, et al.
Publicado: (2022)

Synergistic effect of ibrutinib and CD19 CAR‐T cells on Raji cells in vivo and in vitro
por: Liu, Meijing, et al.
Publicado: (2020)

Molecular fingerprinting of the Indian medicinal plant Strychnos minor Dennst
por: Arumugam, T., et al.
Publicado: (2019)

CAR-T cell potency: from structural elements to vector backbone components
por: Mazinani, Marzieh, et al.
Publicado: (2022)

Conventional CARs versus modular CARs
por: Feldmann, Anja, et al.
Publicado: (2019)

Synergistic Effects of Cabozantinib and EGFR-Specific CAR-NK-92 Cells in Renal Cell Carcinoma
por: Zhang, Qing, et al.
Publicado: (2017)

Synergistic Effects of Zanubrutinib Combined With CD19 CAR-T Cells in Raji Cells in Vitro and in Vivo
por: Ye, Xiupeng, et al.
Publicado: (2022)

Combinatorial CAR design improves target restriction
por: Köksal, Hakan, et al.
Publicado: (2020)

Feasibility of controlling CD38-CAR T cell activity with a Tet-on inducible CAR design
por: Drent, Esther, et al.
Publicado: (2018)

Synergistic Effects of Toxic Elements on Heat Shock Proteins
por: Mahmood, Khalid, et al.
Publicado: (2014)

Asymptomatic congenital ductus arteriosus aneurysm in a newborn: Case by approach
por: Huynh, Thuy, et al.
Publicado: (2023)

Design of electroencephalogram authentication access control to smart car
por: Chen, Yuhua, et al.
Publicado: (2020)

New CAR Designs: Highlights From SOHO 2020
Publicado: (2021)

Corrigendum to “Synergistic Effects of Toxic Elements on Heat Shock Proteins”
por: Mahmood, Khalid, et al.
Publicado: (2015)

Synergistic Activity of Mobile Genetic Element Defences in Streptococcus pneumoniae
por: Kwun, Min Jung, et al.
Publicado: (2019)

Engineering switchable and programmable universal CARs for CAR T therapy
por: Liu, Delong, et al.
Publicado: (2019)

CAR race to cancer immunotherapy: from CAR T, CAR NK to CAR macrophage therapy
por: Pan, Kevin, et al.
Publicado: (2022)

Universal CARs, universal T cells, and universal CAR T cells
por: Zhao, Juanjuan, et al.
Publicado: (2018)

Evaluation of the Elements of Short Hairpin RNAs in Developing shRNA-Containing CAR T Cells
por: Urak, Ryan, et al.
Publicado: (2023)

Intravital imaging reveals synergistic effect of CAR T-cells and radiation therapy in a preclinical immunocompetent glioblastoma model
por: Murty, Surya, et al.
Publicado: (2020)

Generation of human parallel chimeric antigen receptor (pCAR) T cells to achieve synergistic T cell co-stimulation
por: Larcombe-Young, Daniel, et al.
Publicado: (2022)

Buffet Cattle Cars
por: Bass, W. P.
Publicado: (1897)

Long-Lived Afterglow from Elemental Sulfur Powder: Synergistic Effects of Impurity and Structure
por: Guo, Jiaqi, et al.
Publicado: (2022)

Taking Lessons from CAR-T Cells and Going Beyond: Tailoring Design and Signaling for CAR-NK Cells in Cancer Therapy
por: Ruppel, Katharina Eva, et al.
Publicado: (2022)

World powertrains for passenger cars : a review of future trends in engine design & manufacture /
por: Howard, Geoffrey P.
Publicado: (1991)

Cannot write session to /tmp/vufind_sessions/sess_cj758mnud10basdu445grnojt4