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Sirt6 inhibition delays the onset of experimental autoimmune encephalomyelitis by reducing dendritic cell migration

BACKGROUND: Experimental autoimmune encephalomyelitis (EAE) is the most common animal model of multiple sclerosis (MS), a neuroinflammatory and demyelinating disease characterized by multifocal perivascular infiltrates of immune cells. Although EAE is predominantly considered a T helper 1-driven aut...

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Detalles Bibliográficos
Autores principales:	Ferrara, Giovanni, Benzi, Andrea, Sturla, Laura, Marubbi, Daniela, Frumento, Davide, Spinelli, Sonia, Abbotto, Elena, Ivaldi, Federico, von Holtey, Maria, Murone, Maximilien, Nencioni, Alessio, Uccelli, Antonio, Bruzzone, Santina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393881/ https://www.ncbi.nlm.nih.gov/pubmed/32736564 http://dx.doi.org/10.1186/s12974-020-01906-1

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