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Endotrophin, an extracellular hormone, in combination with neoepitope markers of von Willebrand factor improves prediction of mortality in the ECLIPSE COPD cohort
BACKGROUND: Lung epithelial damage, activation of the wound healing cascade, and remodeling of the extracellular matrix (ECM) play a major role in chronic obstructive pulmonary disease (COPD). The pro-peptide of type VI collagen has been identified as the hormone endotrophin. Endotrophin has been sh...
Autores principales: | Rønnow, Sarah R., Langholm, Lasse L., Karsdal, Morten A., Manon-Jensen, Tina, Tal-Singer, Ruth, Miller, Bruce E., Vestbo, Jørgen, Leeming, Diana J., Sand, Jannie M. B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393910/ https://www.ncbi.nlm.nih.gov/pubmed/32731895 http://dx.doi.org/10.1186/s12931-020-01461-6 |
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