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The role of the oncostatin M/OSM receptor β axis in activating dermal microvascular endothelial cells in systemic sclerosis

BACKGROUND: Scleroderma (SSc) is a rare autoimmune disease characterized by vascular impairment and progressive fibrosis of the skin and other organs. Oncostatin M, a member of the IL-6 family, is elevated in SSc serum and was recognized as a significant player in various stages of fibrosis. The goa...

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Detalles Bibliográficos
Autores principales: Marden, G., Wan, Q., Wilks, J., Nevin, K., Feeney, M., Wisniacki, N., Trojanowski, M., Bujor, A., Stawski, L., Trojanowska, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393919/
https://www.ncbi.nlm.nih.gov/pubmed/32736577
http://dx.doi.org/10.1186/s13075-020-02266-0