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Wogonin Induces Apoptosis and Reverses Sunitinib Resistance of Renal Cell Carcinoma Cells via Inhibiting CDK4-RB Pathway

Wogonin, an active component derived from Scutellaria baicalensis, has shown anti-tumor activities in several malignancies. However, the roles of wogonin in RCC cells remain elusive. Here, we explored the effects of wogonin on RCC cells and the underlying mechanisms. We found that wogonin showed sig...

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Detalles Bibliográficos
Autores principales: Wang, Yong, Chen, Shouzhen, Sun, Shuna, Liu, Guangyi, Chen, Lipeng, Xia, Yangyang, Cui, Jianfeng, Wang, Wenfu, Jiang, Xuewen, Zhang, Lei, Zhu, Yaofeng, Zou, Yongxin, Shi, Benkang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7394056/
https://www.ncbi.nlm.nih.gov/pubmed/32792963
http://dx.doi.org/10.3389/fphar.2020.01152