Cargando…
Therapeutic Effects of Tryptanthrin and Tryptanthrin-6-Oxime in Models of Rheumatoid Arthritis
Rheumatoid arthritis (RA) is a chronic autoimmune disease involving joint and bone damage that is mediated in part by proteases and cytokines produced by synovial macrophages and fibroblast-like synoviocytes (FLS). Although current biological therapeutic strategies for RA have been effective in many...
Autores principales: | Kirpotina, Liliya N., Schepetkin, Igor A., Hammaker, Deepa, Kuhs, Amanda, Khlebnikov, Andrei I., Quinn, Mark T. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7394103/ https://www.ncbi.nlm.nih.gov/pubmed/32792961 http://dx.doi.org/10.3389/fphar.2020.01145 |
Ejemplares similares
-
Design, synthesis and biological evaluation of novel O-substituted tryptanthrin oxime derivatives as c-Jun N-terminal kinase inhibitors
por: Schepetkin, Igor A., et al.
Publicado: (2022) -
Novel Tryptanthrin Derivatives with Selectivity as c–Jun N–Terminal Kinase (JNK) 3 Inhibitors
por: Schepetkin, Igor A., et al.
Publicado: (2023) -
Neuroprotective Effects of Tryptanthrin-6-Oxime in a Rat Model of Transient Focal Cerebral Ischemia
por: Plotnikov, Mark B., et al.
Publicado: (2023) -
Experimental and Computational Investigation of the Oxime Bond Stereochemistry in c-Jun N-terminal Kinase 3 Inhibitors 11H-Indeno[1,2-b]quinoxalin-11-one Oxime and Tryptanthrin-6-oxime
por: Matveevskaya, Vladislava V., et al.
Publicado: (2023) -
Synthesis and evaluation of the antiplasmodial activity of tryptanthrin derivatives
por: Onambele, Liliane Abodo, et al.
Publicado: (2015)