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Auditory and Olfactory Deficits in Essential Tremor – Review of the Current Evidence

BACKGROUND: Essential tremor (ET) is the most common adult movement disorder, characterized by several motor and increasingly well recognized non-motor symptoms. Sensory deficits, such as hearing impairment and olfactory dysfunction, are amongst them. This review analyzes the available evidence of t...

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Autor principal: Sengul, Yildizhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ubiquity Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7394198/
https://www.ncbi.nlm.nih.gov/pubmed/32775017
http://dx.doi.org/10.5334/tohm.57
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author Sengul, Yildizhan
author_facet Sengul, Yildizhan
author_sort Sengul, Yildizhan
collection PubMed
description BACKGROUND: Essential tremor (ET) is the most common adult movement disorder, characterized by several motor and increasingly well recognized non-motor symptoms. Sensory deficits, such as hearing impairment and olfactory dysfunction, are amongst them. This review analyzes the available evidence of these sensory deficits and their possible mechanistic basis in patients with ET. METHOD: A PubMed literature search on the topic was performed in the May 2019 database. RESULTS: Nineteen articles on hearing impairment and olfactory dysfunction in ET patients were identified. The prevalence of hearing impairment is higher in ET patients than healthy controls or Parkinson disease. Cochlear pathologies are suggested as the underlying cause, but there is still a lack of information about retrocochlear pathologies and central auditory processing. Reports on olfactory dysfunction have conflicting results. The presence of mild olfactory dysfunction in ET was suggested. Conflicting results may be due to the lack of consideration of the disease’s heterogeneity, but according to recent data, most studies do not find prominent evidence of olfactory loss in ET. CONCLUSION: Although there is increasing interest in studies on non-motor symptoms in ET, there are few studies on sensory deficits, which are of particularly high prevalence. More studies are needed on to investigate the basis of non-motor symptoms, including sensory deficits.
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spelling pubmed-73941982020-08-07 Auditory and Olfactory Deficits in Essential Tremor – Review of the Current Evidence Sengul, Yildizhan Tremor Other Hyperkinet Mov (N Y) Review BACKGROUND: Essential tremor (ET) is the most common adult movement disorder, characterized by several motor and increasingly well recognized non-motor symptoms. Sensory deficits, such as hearing impairment and olfactory dysfunction, are amongst them. This review analyzes the available evidence of these sensory deficits and their possible mechanistic basis in patients with ET. METHOD: A PubMed literature search on the topic was performed in the May 2019 database. RESULTS: Nineteen articles on hearing impairment and olfactory dysfunction in ET patients were identified. The prevalence of hearing impairment is higher in ET patients than healthy controls or Parkinson disease. Cochlear pathologies are suggested as the underlying cause, but there is still a lack of information about retrocochlear pathologies and central auditory processing. Reports on olfactory dysfunction have conflicting results. The presence of mild olfactory dysfunction in ET was suggested. Conflicting results may be due to the lack of consideration of the disease’s heterogeneity, but according to recent data, most studies do not find prominent evidence of olfactory loss in ET. CONCLUSION: Although there is increasing interest in studies on non-motor symptoms in ET, there are few studies on sensory deficits, which are of particularly high prevalence. More studies are needed on to investigate the basis of non-motor symptoms, including sensory deficits. Ubiquity Press 2020-06-09 /pmc/articles/PMC7394198/ /pubmed/32775017 http://dx.doi.org/10.5334/tohm.57 Text en Copyright: © 2020 The Author(s) http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International License (CC-BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. See http://creativecommons.org/licenses/by/4.0/.
spellingShingle Review
Sengul, Yildizhan
Auditory and Olfactory Deficits in Essential Tremor – Review of the Current Evidence
title Auditory and Olfactory Deficits in Essential Tremor – Review of the Current Evidence
title_full Auditory and Olfactory Deficits in Essential Tremor – Review of the Current Evidence
title_fullStr Auditory and Olfactory Deficits in Essential Tremor – Review of the Current Evidence
title_full_unstemmed Auditory and Olfactory Deficits in Essential Tremor – Review of the Current Evidence
title_short Auditory and Olfactory Deficits in Essential Tremor – Review of the Current Evidence
title_sort auditory and olfactory deficits in essential tremor – review of the current evidence
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7394198/
https://www.ncbi.nlm.nih.gov/pubmed/32775017
http://dx.doi.org/10.5334/tohm.57
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