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Comprehensive analyses of immunodynamics and immunoreactivity in response to treatment in ALK-positive non-small-cell lung cancer
BACKGROUND: EML4-ALK is a distinct molecular entity that is highly sensitive to ALK tyrosine kinase inhibitors (TKIs). Immune checkpoint inhibitors (ICIs) have not proved efficacy in ALK-positive non-small cell lung cancer so far. In this study, we performed a mouse clinical trial using EML4-ALK tra...
Autores principales: | Pyo, Kyoung-Ho, Lim, Sun Min, Park, Chae-Won, Jo, Ha-Ni, Kim, Jae Hwan, Yun, Mi-Ran, Kim, Dohee, Xin, Chun-Feng, Lee, Wongeun, Gheorghiu, Bianca, Hong, Min Hee, Kim, Hye Ryun, Shim, Hyo Sup, Jang, Mi, Lee, Sung Sook, Cho, Byoung Chul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7394300/ https://www.ncbi.nlm.nih.gov/pubmed/32727812 http://dx.doi.org/10.1136/jitc-2020-000970 |
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