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Model-based analysis of chromatin interactions from dCas9-Based CAPTURE-3C-seq

Deciphering long-range chromatin interactions is critical for understanding temporal and tissue-specific gene expression regulated by cis- and trans-acting factors. By combining the chromosome conformation capture (3C) and biotinylated dCas9 system, we previously established a method CAPTURE-3C-seq...

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Detalles Bibliográficos
Autores principales: Chen, Yong, Wang, Yunfei, Liu, Xin, Xu, Jian, Zhang, Michael Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7394367/
https://www.ncbi.nlm.nih.gov/pubmed/32735574
http://dx.doi.org/10.1371/journal.pone.0236666

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