CRL4(Cdt2) ubiquitin ligase regulates Dna2 and Rad16 (XPF) nucleases by targeting Pxd1 for degradation

Structure-specific endonucleases (SSEs) play key roles in DNA replication, recombination, and repair. SSEs must be tightly regulated to ensure genome stability but their regulatory mechanisms remain incompletely understood. Here, we show that in the fission yeast Schizosaccharomyces pombe, the activ...

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Detalles Bibliográficos
Autores principales: Zhang, Jia-Min, Zheng, Jin-Xin, Ding, Yue-He, Zhang, Xiao-Ran, Suo, Fang, Ren, Jing-Yi, Dong, Meng-Qiu, Du, Li-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7394458/
https://www.ncbi.nlm.nih.gov/pubmed/32692737
http://dx.doi.org/10.1371/journal.pgen.1008933

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7394458/
https://www.ncbi.nlm.nih.gov/pubmed/32692737
http://dx.doi.org/10.1371/journal.pgen.1008933

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