Regulation of BMP4/Dpp retrotranslocation and signaling by deglycosylation

During endoplasmic reticulum-associated degradation (ERAD), the cytoplasmic enzyme N-glycanase 1 (NGLY1) is proposed to remove N-glycans from misfolded N-glycoproteins after their retrotranslocation from the ER to the cytosol. We previously reported that NGLY1 regulates Drosophila BMP signaling in a...

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Detalles Bibliográficos
Autores principales: Galeone, Antonio, Adams, Joshua M, Matsuda, Shinya, Presa, Maximiliano F, Pandey, Ashutosh, Han, Seung Yeop, Tachida, Yuriko, Hirayama, Hiroto, Vaccari, Thomas, Suzuki, Tadashi, Lutz, Cathleen M, Affolter, Markus, Zuberi, Aamir, Jafar-Nejad, Hamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7394544/
https://www.ncbi.nlm.nih.gov/pubmed/32720893
http://dx.doi.org/10.7554/eLife.55596

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