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Comparison of Patient Susceptibility Genes Across Breast Cancer: Implications for Prognosis and Therapeutic Outcomes

Hereditary breast cancer syndromes affect a small (10–15% of cases) but significant group of patients. BRCA1 and BRCA2 are the most familiar and well-studied genes associated with inherited breast cancer. However, mutations in the high-penetrance genes, TP53, PTEN, CDH1, MSH1, MLH1, MSH6, PMS2, PALB...

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Detalles Bibliográficos
Autores principales: Peleg Hasson, Shira, Menes, Tehillah, Sonnenblick, Amir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7394592/
https://www.ncbi.nlm.nih.gov/pubmed/32801835
http://dx.doi.org/10.2147/PGPM.S233485