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Wernicke’s Encephalopathy: Typical Disease with an Atypical Clinicoradiological Manifestation
Wernicke’s encephalopathy is an acute neurological disorder caused due to thiamine deficiency. It is characterized by a triad of confusion, ataxia, and ophthalmoplegia. Wernicke’s encephalopathy can present with atypical clinical manifestations, particularly in setting of nonalcoholic background. Ou...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Thieme Medical and Scientific Publishers Private Ltd.
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7394616/ https://www.ncbi.nlm.nih.gov/pubmed/32753819 http://dx.doi.org/10.1055/s-0040-1713334 |
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author | Verma, Rajesh Kumar, Chetan |
author_facet | Verma, Rajesh Kumar, Chetan |
author_sort | Verma, Rajesh |
collection | PubMed |
description | Wernicke’s encephalopathy is an acute neurological disorder caused due to thiamine deficiency. It is characterized by a triad of confusion, ataxia, and ophthalmoplegia. Wernicke’s encephalopathy can present with atypical clinical manifestations, particularly in setting of nonalcoholic background. Our patient manifested with clinical complaints of acute drowsiness, speech difficulty, and ataxia. Magnetic resonance imaging of the brain revealed T2 hyperintensity in bilateral medial thalami, globus pallidus, periaqueductal gray matter, dorsal pons, and dorsal medulla. The diagnosis of Wernicke’s encephalopathy was entertained and he well responded to parental thiamine therapy. The clinician should be aware about atypical presentation of Wernicke’s encephalopathy. |
format | Online Article Text |
id | pubmed-7394616 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Thieme Medical and Scientific Publishers Private Ltd. |
record_format | MEDLINE/PubMed |
spelling | pubmed-73946162020-08-03 Wernicke’s Encephalopathy: Typical Disease with an Atypical Clinicoradiological Manifestation Verma, Rajesh Kumar, Chetan J Neurosci Rural Pract Wernicke’s encephalopathy is an acute neurological disorder caused due to thiamine deficiency. It is characterized by a triad of confusion, ataxia, and ophthalmoplegia. Wernicke’s encephalopathy can present with atypical clinical manifestations, particularly in setting of nonalcoholic background. Our patient manifested with clinical complaints of acute drowsiness, speech difficulty, and ataxia. Magnetic resonance imaging of the brain revealed T2 hyperintensity in bilateral medial thalami, globus pallidus, periaqueductal gray matter, dorsal pons, and dorsal medulla. The diagnosis of Wernicke’s encephalopathy was entertained and he well responded to parental thiamine therapy. The clinician should be aware about atypical presentation of Wernicke’s encephalopathy. Thieme Medical and Scientific Publishers Private Ltd. 2020-07 2020-06-12 /pmc/articles/PMC7394616/ /pubmed/32753819 http://dx.doi.org/10.1055/s-0040-1713334 Text en https://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited. |
spellingShingle | Verma, Rajesh Kumar, Chetan Wernicke’s Encephalopathy: Typical Disease with an Atypical Clinicoradiological Manifestation |
title | Wernicke’s Encephalopathy: Typical Disease with an Atypical Clinicoradiological Manifestation |
title_full | Wernicke’s Encephalopathy: Typical Disease with an Atypical Clinicoradiological Manifestation |
title_fullStr | Wernicke’s Encephalopathy: Typical Disease with an Atypical Clinicoradiological Manifestation |
title_full_unstemmed | Wernicke’s Encephalopathy: Typical Disease with an Atypical Clinicoradiological Manifestation |
title_short | Wernicke’s Encephalopathy: Typical Disease with an Atypical Clinicoradiological Manifestation |
title_sort | wernicke’s encephalopathy: typical disease with an atypical clinicoradiological manifestation |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7394616/ https://www.ncbi.nlm.nih.gov/pubmed/32753819 http://dx.doi.org/10.1055/s-0040-1713334 |
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