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Wernicke’s Encephalopathy: Typical Disease with an Atypical Clinicoradiological Manifestation

Wernicke’s encephalopathy is an acute neurological disorder caused due to thiamine deficiency. It is characterized by a triad of confusion, ataxia, and ophthalmoplegia. Wernicke’s encephalopathy can present with atypical clinical manifestations, particularly in setting of nonalcoholic background. Ou...

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Autores principales: Verma, Rajesh, Kumar, Chetan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Thieme Medical and Scientific Publishers Private Ltd. 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7394616/
https://www.ncbi.nlm.nih.gov/pubmed/32753819
http://dx.doi.org/10.1055/s-0040-1713334
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author Verma, Rajesh
Kumar, Chetan
author_facet Verma, Rajesh
Kumar, Chetan
author_sort Verma, Rajesh
collection PubMed
description Wernicke’s encephalopathy is an acute neurological disorder caused due to thiamine deficiency. It is characterized by a triad of confusion, ataxia, and ophthalmoplegia. Wernicke’s encephalopathy can present with atypical clinical manifestations, particularly in setting of nonalcoholic background. Our patient manifested with clinical complaints of acute drowsiness, speech difficulty, and ataxia. Magnetic resonance imaging of the brain revealed T2 hyperintensity in bilateral medial thalami, globus pallidus, periaqueductal gray matter, dorsal pons, and dorsal medulla. The diagnosis of Wernicke’s encephalopathy was entertained and he well responded to parental thiamine therapy. The clinician should be aware about atypical presentation of Wernicke’s encephalopathy.
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spelling pubmed-73946162020-08-03 Wernicke’s Encephalopathy: Typical Disease with an Atypical Clinicoradiological Manifestation Verma, Rajesh Kumar, Chetan J Neurosci Rural Pract Wernicke’s encephalopathy is an acute neurological disorder caused due to thiamine deficiency. It is characterized by a triad of confusion, ataxia, and ophthalmoplegia. Wernicke’s encephalopathy can present with atypical clinical manifestations, particularly in setting of nonalcoholic background. Our patient manifested with clinical complaints of acute drowsiness, speech difficulty, and ataxia. Magnetic resonance imaging of the brain revealed T2 hyperintensity in bilateral medial thalami, globus pallidus, periaqueductal gray matter, dorsal pons, and dorsal medulla. The diagnosis of Wernicke’s encephalopathy was entertained and he well responded to parental thiamine therapy. The clinician should be aware about atypical presentation of Wernicke’s encephalopathy. Thieme Medical and Scientific Publishers Private Ltd. 2020-07 2020-06-12 /pmc/articles/PMC7394616/ /pubmed/32753819 http://dx.doi.org/10.1055/s-0040-1713334 Text en https://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited.
spellingShingle Verma, Rajesh
Kumar, Chetan
Wernicke’s Encephalopathy: Typical Disease with an Atypical Clinicoradiological Manifestation
title Wernicke’s Encephalopathy: Typical Disease with an Atypical Clinicoradiological Manifestation
title_full Wernicke’s Encephalopathy: Typical Disease with an Atypical Clinicoradiological Manifestation
title_fullStr Wernicke’s Encephalopathy: Typical Disease with an Atypical Clinicoradiological Manifestation
title_full_unstemmed Wernicke’s Encephalopathy: Typical Disease with an Atypical Clinicoradiological Manifestation
title_short Wernicke’s Encephalopathy: Typical Disease with an Atypical Clinicoradiological Manifestation
title_sort wernicke’s encephalopathy: typical disease with an atypical clinicoradiological manifestation
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7394616/
https://www.ncbi.nlm.nih.gov/pubmed/32753819
http://dx.doi.org/10.1055/s-0040-1713334
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