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Hypovitaminosis D, Low Bone Mineral Density, and Diabetes Mellitus as Probable Risk Factors for Benign Paroxysmal Positional Vertigo in the Elderly

Introduction  Studies have found that elderly patients with benign paroxysmal positional vertigo (BPPV) may present low levels of vitamin D (25 (OH) D), changes in bone mineral density, and diabetes mellitus (DM). Objective : To investigate the possible association between BPPV, bone mineral density...

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Autores principales: Bazoni, Jessica Aparecida, Ciquinato, Daiane Soares Almeida, Marquez, Audrey de Souza, Costa, Viviane de Souza Pinho, Marchiori, Glória de Moraes, Marchiori, Luciana Lozza de Moraes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Thieme Revinter Publicações Ltda 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7394622/
https://www.ncbi.nlm.nih.gov/pubmed/32754236
http://dx.doi.org/10.1055/s-0039-1700583
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author Bazoni, Jessica Aparecida
Ciquinato, Daiane Soares Almeida
Marquez, Audrey de Souza
Costa, Viviane de Souza Pinho
Marchiori, Glória de Moraes
Marchiori, Luciana Lozza de Moraes
author_facet Bazoni, Jessica Aparecida
Ciquinato, Daiane Soares Almeida
Marquez, Audrey de Souza
Costa, Viviane de Souza Pinho
Marchiori, Glória de Moraes
Marchiori, Luciana Lozza de Moraes
author_sort Bazoni, Jessica Aparecida
collection PubMed
description Introduction  Studies have found that elderly patients with benign paroxysmal positional vertigo (BPPV) may present low levels of vitamin D (25 (OH) D), changes in bone mineral density, and diabetes mellitus (DM). Objective : To investigate the possible association between BPPV, bone mineral density, hypovitaminosis D, 25 (OH) D and DM. Methods  The sample consisted of 109 elderly subjects. The BPPV was verified by a standardized questionnaire and the Dix-Hallpike maneuver. Blood samples were collected for the investigation of 25 (OH) D serum levels. The bone mineral density was evaluated by means of a densitometer. Diabetes mellitus verification was performed using a self-reported questionnaire. Results  Of the 109 participants, 17 had BPPV. There was a statistically significant difference between BPPV and gender ( p  = 0.027, phi = 0.222), with female representing 88.2% of those with BPPV. In the group with BPPV, there was a statistically significant difference for the amount of vitamin D found ( p  = 0.001) and for age ( p  = 0.001). In the elderly group with DM and BPPV, a difference was found for the standard deviation of the femur ( p  = 0.022) with posthoc Dunn, identifying the difference between diabetics with and without BPPV ( p  = 0.047). Conclusion  Although no association was found (25 (OH) D levels) with BPPV in the general population of this study, it was observed that there was an association with bone mineral density in the elderly group with DM and BPPV, and, in the group with BPPV, there was an association between the amount of vitamin D and age.
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spelling pubmed-73946222020-08-03 Hypovitaminosis D, Low Bone Mineral Density, and Diabetes Mellitus as Probable Risk Factors for Benign Paroxysmal Positional Vertigo in the Elderly Bazoni, Jessica Aparecida Ciquinato, Daiane Soares Almeida Marquez, Audrey de Souza Costa, Viviane de Souza Pinho Marchiori, Glória de Moraes Marchiori, Luciana Lozza de Moraes Int Arch Otorhinolaryngol Introduction  Studies have found that elderly patients with benign paroxysmal positional vertigo (BPPV) may present low levels of vitamin D (25 (OH) D), changes in bone mineral density, and diabetes mellitus (DM). Objective : To investigate the possible association between BPPV, bone mineral density, hypovitaminosis D, 25 (OH) D and DM. Methods  The sample consisted of 109 elderly subjects. The BPPV was verified by a standardized questionnaire and the Dix-Hallpike maneuver. Blood samples were collected for the investigation of 25 (OH) D serum levels. The bone mineral density was evaluated by means of a densitometer. Diabetes mellitus verification was performed using a self-reported questionnaire. Results  Of the 109 participants, 17 had BPPV. There was a statistically significant difference between BPPV and gender ( p  = 0.027, phi = 0.222), with female representing 88.2% of those with BPPV. In the group with BPPV, there was a statistically significant difference for the amount of vitamin D found ( p  = 0.001) and for age ( p  = 0.001). In the elderly group with DM and BPPV, a difference was found for the standard deviation of the femur ( p  = 0.022) with posthoc Dunn, identifying the difference between diabetics with and without BPPV ( p  = 0.047). Conclusion  Although no association was found (25 (OH) D levels) with BPPV in the general population of this study, it was observed that there was an association with bone mineral density in the elderly group with DM and BPPV, and, in the group with BPPV, there was an association between the amount of vitamin D and age. Thieme Revinter Publicações Ltda 2020-07 2019-12-13 /pmc/articles/PMC7394622/ /pubmed/32754236 http://dx.doi.org/10.1055/s-0039-1700583 Text en https://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited.
spellingShingle Bazoni, Jessica Aparecida
Ciquinato, Daiane Soares Almeida
Marquez, Audrey de Souza
Costa, Viviane de Souza Pinho
Marchiori, Glória de Moraes
Marchiori, Luciana Lozza de Moraes
Hypovitaminosis D, Low Bone Mineral Density, and Diabetes Mellitus as Probable Risk Factors for Benign Paroxysmal Positional Vertigo in the Elderly
title Hypovitaminosis D, Low Bone Mineral Density, and Diabetes Mellitus as Probable Risk Factors for Benign Paroxysmal Positional Vertigo in the Elderly
title_full Hypovitaminosis D, Low Bone Mineral Density, and Diabetes Mellitus as Probable Risk Factors for Benign Paroxysmal Positional Vertigo in the Elderly
title_fullStr Hypovitaminosis D, Low Bone Mineral Density, and Diabetes Mellitus as Probable Risk Factors for Benign Paroxysmal Positional Vertigo in the Elderly
title_full_unstemmed Hypovitaminosis D, Low Bone Mineral Density, and Diabetes Mellitus as Probable Risk Factors for Benign Paroxysmal Positional Vertigo in the Elderly
title_short Hypovitaminosis D, Low Bone Mineral Density, and Diabetes Mellitus as Probable Risk Factors for Benign Paroxysmal Positional Vertigo in the Elderly
title_sort hypovitaminosis d, low bone mineral density, and diabetes mellitus as probable risk factors for benign paroxysmal positional vertigo in the elderly
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7394622/
https://www.ncbi.nlm.nih.gov/pubmed/32754236
http://dx.doi.org/10.1055/s-0039-1700583
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