Neural Stem Cells Improve the Delivery of Oncolytic Chimeric Orthopoxvirus in a Metastatic Ovarian Cancer Model

Oncolytic virotherapy represents a promising approach for treating recurrent and/or drug-resistant ovarian cancer. However, its successful application in the clinic has been hampered by rapid immune-mediated clearance, which reduces viral delivery to the tumor. Patient-derived mesenchymal stem cells...

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Detalles Bibliográficos
Autores principales: Hammad, Mohamed, Cornejo, Yvonne R., Batalla-Covello, Jennifer, Majid, Asma Abdul, Burke, Connor, Liu, Zheng, Yuan, Yate-Ching, Li, Min, Dellinger, Thanh H., Lu, Jianming, Chen, Nanhai G., Fong, Yuman, Aboody, Karen S., Mooney, Rachael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7394740/
https://www.ncbi.nlm.nih.gov/pubmed/32775617
http://dx.doi.org/10.1016/j.omto.2020.07.002

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